Results 31 to 40 of about 6,809,463 (257)

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

A Survey of Green Networking Research [PDF]

open access: yes, 2010
Reduction of unnecessary energy consumption is becoming a major concern in wired networking, because of the potential economical benefits and of its expected environmental impact.
Bianzino, Aruna Prem   +3 more
core  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Report. [PDF]

open access: yes, 2013
v.1946/1947 : http://babel.hathitrust.org/cgi/pt?id=mdp.39015005666451;view=2up;ui=fullscreen#page/n0/mode/2up1948 : http://babel.hathitrust.org/cgi/pt?id=mdp.39015035433989;view=2up;ui=fullscreen#page/n0/mode/2up1950 : http://babel.hathitrust.org/cgi/pt?
University of Michigan. Survey Research Center
core  

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Public Perceptions of the Midwest’s Pavements - Minnesota - Phase I (Winter Ride) [PDF]

open access: yes, 1997
The Minnesota Winter Ride Survey was designed to gauge the extent to which motorists were tolerant of the rougher ride of pavements on rural two-lane highways in the winter. Survey objectives, therefore, were centered around this focal question of winter
Marquette University, Department of Civil, Construction, and Environmental Engineering   +1 more
core   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

Using Survey Research to Evaluate Communications Campaigns [PDF]

open access: yes, 2004
The use of survey research is perhaps the best example of the need to plan for communications evaluation because it is costly and highly sensitive to three elements of campaign design: your audience, your goal, and your campaign's communications budget ...

core  

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