Results 91 to 100 of about 8,868,074 (395)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Accuracy and validity of maximum depositional ages in light of tandem (laser ablation and isotope dilution) U–Pb detrital zircon geochronology, including results from northern Alaska [PDF]
Sound geologic reasoning underpins detrital zircon (DZ) maximum depositional ages (MDAs) via the principle of inclusions, although interpreting in situ U–Pb date distributions requires many geologically, analytically, and statistically driven decisions ...
T. M. Herriott +4 more
doaj +1 more source
AbstractIf a graph has bounded clique number and sufficiently large chromatic number, what can we say about its induced subgraphs? András Gyárfás made a number of challenging conjectures about this in the early 1980s, which have remained open until recently; but in the last few years there has been substantial progress. This is a survey of where we are
Alex Scott, Paul Seymour
openaire +4 more sources
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Selection functions of large spectroscopic surveys
Context. Large spectroscopic surveys open the way to explore our Galaxy. In order to use the data from these surveys to understand the Galactic stellar population, we need to be sure that stars contained in a survey are a representative subset of the ...
Hekker, Saskia, Mints, Alexey
core +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Weak Lensing Science, Surveys, and Systematics
Weak gravitational lensing is one of the key probes of the cosmological model, dark energy, and dark matter, providing insight into both the cosmic expansion history and large scale structure growth history.
Das, Sudeep +3 more
core +1 more source
There is an established methodology for conducting survey research that aims to ensure rigorous research and robust outputs. With the advent of easy-to-use online survey platforms, however, the quality of survey studies has declined.
H. Ball
semanticscholar +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source

