Results 201 to 210 of about 4,743,163 (348)

The ALMA-CRISTAL Survey [PDF]

open access: diamond
Ryota Ikeda   +26 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Repeated biannual cross-sectional surveys in primary schools set baseline seasonal and spatial surveillance for malaria and schistosomiasis in the Shire Valley Transformation Programme (SVTP), Malawi. [PDF]

open access: yesCurr Res Parasitol Vector Borne Dis
Kapolo P   +11 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Community consultation for exception from informed consent studies: are market research surveys representative of the target community populations? [PDF]

open access: yesTrauma Surg Acute Care Open
Stephens SW   +18 more
europepmc   +1 more source

Factuality of Large Language Models: A Survey [PDF]

open access: gold
Yuxia Wang   +6 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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