Results 211 to 220 of about 8,868,074 (395)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Observations of extreme dehydration and rehydration leading to recovery of a threatened California tiger salamander

California Fish and Wildlife Journal, 2022
Zachary A. Cava, Kyla M. Garten, Sarah M. Foster, Jeff A. Alvarez   +3 more
doaj   +1 more source

Health monitoring at the Robert Koch Institute - Effects of a change in study design on sample composition and prevalence estimates due to the start of the 'Health in Germany' Panel. [PDF]

J Health Monit
Mauz E, Vogelgesang F, Damerow S, Schienkiewitz A, Michalski N, Gaertner B, Allen J, Baumert J, Du Y, Kuhnert R, Lemcke J, Scheufele R, Rosario AS.   +12 more
europepmc   +1 more source

CAUSAL INFERENCE ON EDUCATION POLICIES: A SURVEY OF EMPIRICAL STUDIES USING PISA, TIMSS AND PIRLS [PDF]

, 2017
José Manuel Cordero Ferrera, Víctor Cristóbal, Daniel Santín González   +2 more
openalex   +1 more source

Mental disorders among college students in the World Health Organization World Mental Health Surveys

Psychological Medicine, 2016
R. Auerbach, J. Alonso, W. Axinn, P. Cuijpers, D. Ebert, J. G. Green, I. Hwang, R. Kessler, H. Liu, P. Mortier, M. Nock, S. Pinder-Amaker, N. Sampson, S. Aguilar-Gaxiola, A. Al-Hamzawi, L. Andrade, C. Benjet, J. Caldas-de-Almeida, K. Demyttenaere, S. Florescu, G. de Girolamo, O. Gureje, J. Haro, E. Karam, A. Kiejna, V. Kovess-Masfety, S. Lee, J. Mcgrath, Siobhan O'Neill, B. Pennell, K. Scott, M. ten Have, Y. Torres, A. Zaslavsky, Z. Zarkov, R. Bruffaerts   +35 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Method matters: Use of thermal-imaging drones to assess the assumptions of density estimation techniques. [PDF]

Ecol Appl
Delaney DM, Harms TM, Dinsmore SJ.
europepmc   +1 more source

Pristine dwarf galaxy survey – I. A detailed photometric and spectroscopic study of the very metal-poor Draco II satellite [PDF]

, 2018
Nicolas Longeard, Nicolas F. Martin, Else Starkenburg, Rodrigo Ibata, Michelle Collins, Marla Geha, Benjamin P. M. Laevens, R. Michael Rich, David S. Aguado, Anke Arentsen, R. G. Carlberg, Patrick Côté, V. Hill, P. Jablonka, J. I. Gónzalez Hernández, Julio F. Navarro, Rubén Sánchez-Janssen, Eline Tolstoy, Kim A. Venn, Kris Youakim   +19 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Nationwide Temporal Dynamics of Mammal Communities Across South Korea: Dominance Shifts and Predator-Prey Implications. [PDF]

Animals (Basel)
Yi T, Kim TG, Lee BK, Park S, Park J, Lee J.   +5 more
europepmc   +1 more source