Results 251 to 260 of about 8,364,634 (343)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Survey Modalities and COVID-19 Vaccine Uptake in Vietnamese Americans: Cross-Sectional Study.

JMIR Public Health Surveill
Nguyen C, Le A, Yeh P, King B, Nguyen A, Diep J, Nguyen BM.   +6 more
europepmc   +1 more source

Small Area Estimation of Education Levels in Low- and Middle-Income Countries. [PDF]

Ann Appl Stat
Wu Y, Dharamshi A, Wakefield J.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Avoidant-Restrictive Food Intake Disorder in Patients With Gastrointestinal Disorders: A Systematic Review. [PDF]

J Hum Nutr Diet
Henriksen SB, Hornemann C, Hulgaard DR.
europepmc   +1 more source

Need for universal eye health for refractive error services in India. [PDF]

Indian J Ophthalmol
Vashist P.
europepmc   +1 more source

The Persistent Gap in Mass Drug Administration Uptake Among Known Microfilaria-Positive Individuals in India's Lymphatic Filariasis Elimination Program: A Call for Strengthened Follow-Up Strategies. [PDF]

Cureus
Selvaraju E.
europepmc   +1 more source

Trends in ethnic disparities in reproductive, maternal, neonatal and child health interventions and the role of social investment and inclusive policies: a mixed-methods study in Ecuador, 2004-2018. [PDF]

BMJ Open
Rios-Quituizaca P, Endara-Mina J, Ferreira LZ, Armenta-Paulino N.   +3 more
europepmc   +1 more source