Results 111 to 120 of about 47,870 (296)

An Algorithm for Identifying the Possibilities of Cascading Failure Processes and Their Development Trajectories in Electric Power Systems

open access: yesAlgorithms
Every year, electric power systems (EPSs) experience accidents resulting in static and dynamic instability, as well as power supply disruptions. Accidents evolve along various trajectories and sometimes can exhibit a cascading effect.
Pavel Ilyushin   +3 more
doaj   +1 more source

Multi-attribute tradespace exploration for survivability [PDF]

open access: yes, 2009
Thesis (Ph. D.)--Massachusetts Institute of Technology, Engineering Systems Division, 2009.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Richards, Matthew G
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The Survivability of Symmetrical Hierarchical Networks with Radial Reserve [PDF]

open access: yes, 2008
In this paper we shall consider the Symmetrical Hierarchical Network (SHN) and show that SHN possesses poor properties of survivability. There are several methods for raising the survivability of SHN.
Ahmadi, Mohammad B.
core   +1 more source

Survivability Assessment: Modeling A Recovery Process

open access: yes, 2009
Survivability is the ability of a system to continue operating, in a timely manner, in the presence ofattacks, failures, or accidents. Recovery in survivability is a process of a system to heal or recover from damageas early as possible to fulfill its ...
Abdullah, Azween   +1 more
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Survivability of infected A549 cells.

open access: yes, 2016
The survivability of infected A549 cells which received pre-infection and pre + post-infection treatment was significantly higher than the control. Survivability of non-infected A549 cells was calculated as 100% and thus not shown in the figure.
Ong Guang-Han (3157656)   +5 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

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