Results 231 to 240 of about 47,870 (296)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Intrathecal pump therapy: a retrospective cohort with over 1500 pump-years of follow-up. [PDF]

Brain Spine
Matthijs V, Vandamme S, Nagels W, De Coster O, Hanssens K, Maenhoudt W, Van Lerbeirghe J, Van Damme O, Vanhauwaert D.   +8 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

O-RAID: a satellite constellation architecture for ultra-resilient global data backup. [PDF]

Sci Rep
Meegama RGN.
europepmc   +1 more source

Bioactive metabolites of UV-resistant Streptomyces alkaliterrae CH-8 and their antioxidant and antibiofilm potential. [PDF]

Sci Rep
Alam T, Din SU, Ahmad A, Ali M, Badshah M, Khan S, Hasan F, Farman M, Shah AA.   +8 more
europepmc   +1 more source

Geospatial Analysis of Breast Cancer Incidence, Mortality, and Access to Screening in Rural and Appalachian Virginia. [PDF]

J Appalach Health
Osher J, Brown C, Nichols P, Ayubi T, Powers J.   +4 more
europepmc   +1 more source

Bridging the gaps in prolonged casualty care: the Prolonged Evacuation Transport Team (PETT) programme. [PDF]

BMJ Mil Health
Ingram BJ, Parker P, Kucaba G, Silcox J, Guła P.   +4 more
europepmc   +1 more source

DNA damage at an early developmental stage affects neurodevelopment in sterlet (Acipenser ruthenus). [PDF]

BMC Biol
Dey A, Rzepkowska M, Fajkowska M, Franěk R, Steinbach C, Pšenička M, Šindelka R, Flajšhans M, Gazo I.   +8 more
europepmc   +1 more source