Results 111 to 120 of about 3,992,788 (314)

Survival

, 2014
These data were collected from a laboratory experiment. Abbreviations used for column headings are described below. LarvaeID - a distinct code for the individual described; MotherID - a distinct code for the female that laid the clutch described ...
Martin Stevens (456599), Chris Mitchell (3316278), Winters, Anne E., Simon P. Blomberg (215995), Blomberg, Simon P., Blount, Jonathan D., Jonathan D. Blount (322880), Stevens, Martin, Mitchell, Chris, Anne E. Winters (847101)   +9 more
core   +1 more source

Recovery of African rhinoceroses since Covid-19 despite poaching

Oryx
Evidence suggests that numbers of African rhinoceroses can increase when annual poaching rates remain below 3.5% of the continental population. In 2020, the global response to the Covid-19 pandemic coincided with a poaching rate of 2.3% (the lowest ...
Sam Ferreira, Michael ‘t Sas-Rolfes, Holly Dublin, Jamie Gaymer, Markus Hofmeyr, Keitumetse Makoma, Yoshan Moodley, Lars Versteege, Dave Balfour   +8 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Business Survival in Portuguese Regions [PDF]

This work addresses the post-entry performance of employer enterprises for seven regions in Portugal, at the NUT II level, by investigating the structural characteristics of survival, using non-parametric and semi-parametric methods, during the period ...
Alcina Nunes, Elsa de Morais Sarmento
core  

Funnel plots for population-based cancer survival: principles, methods and applications.

, 2013
Funnel plots are graphical tools designed to detect excessive variation in performance indicators by simple visual inspection of the data. Their main use in the biomedical domain so far has been to detect publication bias in meta-analyses, but they have ...
Quaresma, M, Coleman, MP, Rachet, B
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Genetic parameters for social effects on survival in cannibalistic layers: Combining survival analysis and a linear animal model

, 2010
Background Mortality due to cannibalism in laying hens is a difficult trait to improve genetically, because censoring is high (animals still alive at the end of the testing period) and it may depend on both the individual itself and the behaviour of its ...
Veerkamp Roel F, Veerkamp, Roel F., Ducrocq, V.P., Ducrocq, Vincent, Bijma, Piter, Bijma Piter, Ducro, B.J., Esther D Ellen, Ellen, Esther D., Bijma, P., Ellen Esther D, Ellen, E.D., Veerkamp, Roel F, Roel F Veerkamp, Ducro, Bart J., Veerkamp, R.F., Vincent Ducrocq, Ducro Bart J, Bart J Ducro, Ducrocq Vincent, Ducro, Bart J, Piter Bijma   +21 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source