Results 81 to 90 of about 7,054,284 (355)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Retrospective Analysis using Deep-Learning Models for Prediction of Survival Outcome and Benefit of Adjuvant Chemotherapy in Stage II/III Colorectal Cancer [PDF]
, 2021 Xingyu Li +4 more
openalex +1 more source
Semi-Competing Risks on A Trivariate Weibull Survival Model
, 2008 A setting of a trivairate survival function using semi-competing risks concept is proposed. The Stanford Heart Transplant data is reanalyzed using a trivariate Weibull distribution model with the proposed survival ...
Lee, Cheng K., Lee, Jenq-Daw
core +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
New Scientist, 2020 How long do viruses like cold, flu and coronavirus survive outside the body? What factors affect this?
openaire +2 more sources
Between-Year Survival and Rank Transitions in Male Black-Capped Chickadees (\u3cem\u3ePoecile Atricapillus\u3c/em\u3e): A Multistate Modeling Approach [PDF]
, 2008 In dominance-structured animal societies, variation in individual fitness is often related to social status. Like many passerine birds, Black-capped Chickadees (Poecile atricapillus) have a short average adult life-expectancy (Ø2 years); however, the ...
Kraus, Cornelia +5 more
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Cross-validation and Peeling Strategies for Survival Bump Hunting using Recursive Peeling Methods
, 2015 We introduce a framework to build a survival/risk bump hunting model with a censored time-to-event response. Our Survival Bump Hunting (SBH) method is based on a recursive peeling procedure that uses a specific survival peeling criterion derived from non/
Choe, Michael +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source