Results 191 to 200 of about 4,846,031 (286)

A Survival Analysis of Pediatric Acute Lymphoblastic Leukemia in Morocco. [PDF]

Asian Pac J Cancer Prev
Bennani Mechita N, Hessissen L, Cherkaoui S, Benmiloud S, Kili A, Abouselham L, Maani K, El Houdzi J, Benajiba N, Lahlimi FE, Khoubila N, El Alaoui El Hanafi M, Ghanam A, Tazi I, Madani A, Belakhel L, Khattab M, Harif M, Youbi M, El Kababri M.   +19 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Time to suicide after psychiatric inpatient discharge: a nationwide Swedish survival analysis. [PDF]

BMC Psychiatry
Berge J, Saric EF, Sellin T, Waern M, Westrin Å, Lindström S.   +5 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

General Overview of Intracranial Meningiomas: 11 Years of Experience in an Oncological Reference Center

Brazilian Neurosurgery
Antônio Carlos de Souza Corrêa, Maíra Piani Couto, Andrew Moraes Monteiro, Bernardo Felipe Santana de Macedo, José Reginaldo Nascimento Brito, Rafael Silva Lemos, Gabrielly Leite Andrade, Manuela Rodrigues Neiva Fernandes   +7 more
doaj   +1 more source

Exploring the recurrence and metastasis of breast invasive ductal carcinoma based on machine learning and survival analysis. [PDF]

Front Oncol
Xu A, Weng X, Zheng J, Cui Q, He G, Cheng Y, Jiang H, Wei M, Zhang S.   +8 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Risk factors and survival analysis of patients with distant metastatic follicular thyroid cancer. [PDF]

Front Endocrinol (Lausanne)
Han N, Si Z, Wang G, Qin G, Lu C, Wang X.   +5 more
europepmc   +1 more source