Results 11 to 20 of about 17,500,545 (334)

Survival Function of the FADD-CASPASE-8-cFLIPL Complex

open access: yesCell Reports, 2012
Caspase-8, the initiator caspase of the death receptor pathway of apoptosis, its adapter molecule, FADD, required for caspase-8 activation, and cFLIPL, a caspase-8-like protein that lacks a catalytic site and blocks caspase-8-mediated apoptosis, are each
Christopher P. Dillon   +8 more
doaj   +2 more sources

Survival of pancreatic cancer cells lacking KRAS function

open access: yesNature Communications, 2017
Pancreatic cancer cells may develop resistance to KRAS inhibitors due to activation of compensatory pathways. In this study, the authors demonstrate that KRAS is dispensable in a subset of pancreatic cancer and that PI3K signalling may have an important ...
Mandar Deepak Muzumdar   +9 more
doaj   +2 more sources

SCYL pseudokinases in neuronal function and survival

open access: yesNeural Regeneration Research, 2016
The generation of mice lacking SCYL1 or SCYL2 and the identification of Scyl1 as the causative gene in the motor neuron disease mouse model muscle deficient (Scyl1 mdf/mdf) demonstrated the importance of the SCY1-like family of protein pseudokinases in ...
Stephane Pelletier
doaj   +3 more sources

Survival functions versus conditional aggregation-based survival functions on discrete space [PDF]

open access: yesInformation Sciences, 2022
In this paper we deal with conditional aggregation-based survival functions recently introduced by Boczek et al. (2020). The concept is worth to study because of its possible implementation in real-life situations and mathematical theory as well. The aim of this paper is the comparison of this new notion with the standard survival function.
Basarik, Stanislav   +2 more
openaire   +3 more sources

Time is function and survival [PDF]

open access: yesANZ Journal of Surgery, 2023
Contains fulltext : 303081.pdf (Publisher’s version ) (Open Access)
Stijn Bekkers   +2 more
openaire   +2 more sources

Ensemble methods for survival function estimation with time-varying covariates [PDF]

open access: yesStatistical Methods in Medical Research, 2020
Survival data with time-varying covariates are common in practice. If relevant, they can improve on the estimation of a survival function. However, the traditional survival forests—conditional inference forest, relative risk forest and random survival ...
Weichi Yao   +3 more
semanticscholar   +1 more source

The Combined Stop-Loss and Quota-Share Reinsurance: Conditional Tail Expectation-Based Optimization from the Joint Perspective of Insurer and Reinsurer

open access: yesRisks, 2021
In the presence of reinsurance, an insurer may effectively reduce its (aggregated) loss by partially ceding such a loss to a reinsurer. Stop-loss and quota-share reinsurance contracts are commonly agreed between these two parties.
Khreshna Syuhada, Arief Hakim, Suci Sari
doaj   +1 more source

Cryptocurrencies and Tokens Lifetime Analysis from 2009 to 2021

open access: yesEconomies, 2022
The success of Bitcoin has spurred emergence of countless alternative coins with some of them shutting down only few weeks after their inception, thus disappearing with millions of dollars collected from enthusiast investors through initial coin offering
Paul Gatabazi   +4 more
doaj   +1 more source

Mathematical model for the analysis of environmental risk factors

open access: yesВестник университета, 2023
The article studies the economic consequences of harmful effects on the environment. A mathematical model has been developed for the analysis of environmental risk factors.
I. V. Sukhorukova, N. A. Chistyakova
doaj   +1 more source

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