Results 51 to 60 of about 1,812,936 (307)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Association Measures in the Bivariate Correlated Frailty Model

Revstat Statistical Journal, 2018
This paper deals with a general bivariate correlated frailty model. This includes the multiplicative as well as the additive frailty effect. The association parameter is studied for the shared as well as the general correlated model. The results for the
Ramesh C. Gupta
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

scikit-survival

, 2019
<p>This release adds the <em>ties</em> argument to <a href="https://scikit-survival.readthedocs.io/en/latest/generated/sksurv.linear_model.CoxPHSurvivalAnalysis.html#sksurv.linear_model.CoxPHSurvivalAnalysis">sksurv.linear_model ...
Sebastian Pölsterl (7338110), Sebastian Pölsterl   +1 more
core   +1 more source

Variable Selection and Model Choice in Structured Survival Models [PDF]

, 2008
In many situations, medical applications ask for flexible survival models that allow to extend the classical Cox-model via the inclusion of time-varying and nonparametric effects.
Hothorn, Torsten, Kneib, Thomas, Hofner, Benjamin   +2 more
core   +1 more source

Population structure and number dynamic characteristics of endangered plant Ormosia hosiei in Sichuan and Guizhou provinces, China

Guangxi Zhiwu
Ormosia hosiei is a rare and endangered plant that is narrowly distributed in South China, with important economic and humanistic values. In order to find out its survival status and the reasons that restrict its development, we investigated the natural ...
WANG Mingbin, WEI Xiaoli, WEI Yi, WANG Man, YU Dalong, YUAN Gangyi   +5 more
doaj   +1 more source

Survival Sounds in Insects: Diversity, Function, and Evolution

Frontiers in Ecology and Evolution, 2021
Insect defense sounds have been reported for centuries. Yet, aside from the well-studied anti-bat sounds of tiger moths, little is understood about the occurrence, function, and evolution of these sounds.
Melanie L. Low, Mairelys Naranjo, Jayne E. Yack   +2 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Predictive significance of the six-minute walk distance for long-term survival in chronic hypercapnic respiratory failure [PDF]

, 2007
Background: The 6-min walk distance ( 6-MWD) is a global marker of functional capacity and prognosis in chronic obstructive pulmonary disease ( COPD), but less explored in other chronic respiratory diseases.
Arzt, Michael, Pfeifer, Michael, Heidtkamp, Felix, Budweiser, Stephan, Schroll, Stephan, Schmidbauer, Kathrin, Heinemann, Frank, Hitzl, Andre P., Jörres, Rudolf A.   +8 more
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source