The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision [PDF]
Calcium (Ca2+) plays an important role in the function and health of neurons. In vertebrate cone photoreceptors, Ca2+ controls photoresponse sensitivity, kinetics, and light adaptation.
Arden +69 more
core +2 more sources
Background Hypersensitivity pneumonitis (HP) is an interstitial lung disease with a better prognosis, on average, than idiopathic pulmonary fibrosis (IPF).
M. Salisbury +15 more
semanticscholar +1 more source
Functional connectivity within glioblastoma impacts overall survival [PDF]
Abstract Background Glioblastoma (GBM; World Health Organization grade IV) assumes a variable appearance on MRI owing to heterogeneous proliferation and infiltration of its cells. As a result, the neurovascular units responsible for functional connectivity (FC) may exist within gross tumor boundaries,
Daniel, Andy GS +9 more
openaire +4 more sources
Semi-Competing Risks on A Trivariate Weibull Survival Model
A setting of a trivairate survival function using semi-competing risks concept is proposed. The Stanford Heart Transplant data is reanalyzed using a trivariate Weibull distribution model with the proposed survival ...
Lee, Cheng K., Lee, Jenq-Daw
core +3 more sources
Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma [PDF]
Copyright @ 2013 Macmillan Publishers Limited. This is the author's accepted manuscript. The final published article is available from the link below.Regulation of cell survival is a key part of the pathogenesis of multiple myeloma (MM).
A Barbarulo +63 more
core +2 more sources
Current evidence for treatment with nusinersen for spinal muscular atrophy : a systematic review [PDF]
Recent discovery of nusinersen, an antisense oligonucleotide drug, has provided encouragement for improving treatment of spinal muscular atrophy. No therapeutic options currently exist for this autosomal recessive motor neuron disorder.
Meylemans, Antoon, De Bleecker, Jan
core +1 more source
Flavonoids for preserving pancreatic beta cell survival and function: A mechanistic review.
Although the currently available antidiabetic medications are effective in managing hyperglycemia, vascular complications are common in diabetic patients.
A. Ghorbani +2 more
semanticscholar +1 more source
Mathematical Properties of the Inverted Topp–Leone Family of Distributions
This article defines an inverted Topp–Leone distribution. Several mathematical properties and maximum likelihood estimation of parameters of this distribution are considered.
Daya K. Nagar +2 more
doaj +1 more source
New Lifetime Alpha Power Rayleigh Weibull Distribution: Structure and Properties
Alpha power transformation family distributions (APT) are considered one of the modern transformations that have received the attention of researchers in the past decade and are concerned with adding a shape parameter.
Zainab Ali Ahmed +2 more
doaj +1 more source
Generalized survival in equilibrium step fluctuations
We investigate the dynamics of a generalized survival probability $S(t,R)$ defined with respect to an arbitrary reference level $R$ (rather than the average) in equilibrium step fluctuations.
A.-L. Barabasi +6 more
core +1 more source

