Results 221 to 230 of about 4,464,251 (309)

Efficiency of Immunological Blood Biomarkers in Predicting Chemotherapy Response and Survival Outcome for Non-Targetable Advanced Non-Small Cell Lung Cancer Patients. [PDF]

Lung Cancer (Auckl)
Lumjiaktase P, Kemawichanurat N, Santiwiwas K, Kuttiyod T, Oranratnachai S, Trachu N, Monnamo N, Khiewngam K, Simmalee K, Reungwetwattana T.   +9 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

A Retrospective Analysis of the Clinicopathological Spectrum and Survival Outcome of Non-Hodgkin Lymphoma From a Tertiary Care Hospital in Saudi Arabia. [PDF]

Cureus
Mahmood N, Aamir S, Alseraye A, Alammari A, Alyahya A, Alammari K, Alahmari S.   +6 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Use of the HOPE score to assess survival outcome of hypothermic cardiac arrest selected by ECLS rewarming. [PDF]

Scand J Trauma Resusc Emerg Med
Hall N, Métrailler-Mermoud J, Rousson V, Conforti C, Dupasquier A, Carron PN, Grabherr S, Schrag B, Kirsch M, Falat C, Delay D, Frochaux V, Pasquier M.   +12 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

High-Dimensional Disease Risk Score for Dealing With Residual Confounding Bias in Estimating Treatment Effects With a Survival Outcome. [PDF]

Pharmacoepidemiol Drug Saf
Hossain MB, Wong H, Sadatsafavi M, Cook VJ, Johnston JC, Karim ME.   +5 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

A spatial multi-omic portrait of survival outcome for clear cell renal cell carcinoma

Meyer L, Engler S, Lutz M, Schraml P, Rutishauser D, Bertolini A, Lienhard M, Beisel C, Singer F, De Souza N, Beerenwinkel N, Moch H, Bodenmiller B.   +12 more
europepmc   +1 more source

Using laxative to recover intestinal function could improve the survival outcome for patients with cardiac arrest: a retrospective cohort study from MIMIC-IV database. [PDF]

J Intensive Care
Duan J, Shi Y, Du Y, Li D, Duan B, Wang G.   +5 more
europepmc   +1 more source