Results 141 to 150 of about 1,877,858 (304)

The incidence and mortality trend of breast cancer among women with registered residence in Xiaoshan District of Hangzhou City in Zhejiang Province from 2014 to 2023

Shanghai yufang yixue
ObjectiveTo analyze the trend of incidence, mortality rate and survival rate of breast cancer among women with registered residence in Xiaoshan District of Hangzhou City in Zhejiang Province from 2014 to 2023, and to provide a basis for improving breast ...
LIN Junying, GAO Yuanyuan, WANG Dongfei, LI Yurong   +3 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Characterization of Drought Stress Responses in Phalaenopsis amabilis Based on Survival Percentage and Stomatal Density

World Journal of Advanced Research and Reviews
The moon orchid [Phalaenopsis amabilis (L.) Blume] is a highly valued ornamental plant designated as one of Indonesia’s national flowers due to its exceptional aesthetic appeal. Despite its economic importance, its growth is strongly influenced by environmental conditions, particularly drought stress. Drought can inhibit various physiological processes,
Hr, Tarisa Livia, Nurcahyani, Endang, Sumardi, Sumardi, Qudus, Hardoko Insan, Irawan, Bambang   +4 more
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Identification of a mutation in the para-sodium channel gene of the cattle tick Rhipicephalus (Boophilus) microplus associated with resistance to synthetic pyrethroid acaricides [PDF]

, 2009
Resistance against synthetic pyrethroid (SP) products for the control of cattle ticks in Australia was detected in the field in 1984, within a very short time of commercial introduction.
Corley, S.W., Jackson, L.A., Jonsson, N.N., Lew-Tabor, A.E., Moolhuijzen, P.M., Morgan, J.A.T.   +5 more
core   +1 more source

MP45-18 PERCENTAGE OF SARCOMATOID HISTOLOGY IS ASSOCIATED WITH SURVIVAL FOR PATIENTS WITH RENAL CELL CARCINOMA [PDF]

Journal of Urology, 2021
Amy Man, Elizabeth Koehne, Hiten Patel, Alessa Aragao, Robert Flanigan, Alex Gorbonos, Gopal Gupta, Michael Woods, Maria Picken, Marcus Quek   +9 more
openaire   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Prognostic Significance of Lymphocyte Percentage and IL-6 Level in Patients Undergoing Radiotherapy for Advanced Lung Cancer

Bezmiâlem Science
Objective: Although most patients with locally advanced lung cancer show a moderate response to chemoradiotherapy, the results are not satisfactory. In lung cancer, lymphocyte percentages and interleukin-6 (IL-6) cytokine levels have been reported to be ...
Kimia ÇEPNİ, Tuğçe DURSUN UÇAR, Tuğçe Hilal UÇGUN, Huriye Senay KIZILTAN   +3 more
doaj   +1 more source

An evaluation of the survival of Atlantic salmon (Salmo salar L.)fry stocked in eight streams in the North West of England. [PDF]

, 1995
Eight streams from the North West of England were stocked with Atlantic salmon (Salmo salar L.) fed fry at densities ranging from 1 to 4/m2 over a period of up to three years to evaluate survival to the end of the first an d second growing periods and ...
Aprahamian, M.W., Farooqi, M.A.
core