Results 91 to 100 of about 8,305,568 (307)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Artemisia vulgaris L. supplementation on development, mortality, and hatching rate of Zebrafish embryo exposed to heat stress during in vitro culture

open access: yesVeterinary Biomedical and Clinical Journal
We investigated the effect of Artemisia vulgaris L. supplementation on Zebrafish embryos exposed to heat stress during in vitro culture. Zebrafish embryos were divided into two groups, namely heat stress (HS; 36oC) and non-heat stress or control (NHS ...
Habib Syaiful Arif Tuska Tuska   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Survival rate of honeybee (Apis mellifera) workers after exposure to sublethal concentrations of imidacloprid [PDF]

open access: yes, 2010
Imidacloprid is a commonly used systemic insecticide which can induce several sublethal effects. Previous research has not shown any increased mortality in bees that were fed with sublethal doses. However, there is very little research conducted with the
Blacquiere, T.
core  

Socio-economic inequalities in survival of patients with prostate cancer: role of age and Gleason grade at diagnosis [PDF]

open access: yes, 2013
In the United Kingdom, survival of prostate cancer patients has improved since the 1990s. A deprivation gap in survival (better survival for the least deprived compared with the most deprived) has been reported but it is not known if differential ...
Morrison David S.   +5 more
core   +2 more sources

Global trends in gallbladder cancer survival: A 30-year analysis of cancer registry data

open access: yesHeliyon
Background: Gallbladder cancer has historically been characterized with a poor prognosis. This study aims to describe the global patterns and temporal trends in gallbladder cancer survival using data from cancer registries.
Yu-Xuan Xiao   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Nonparametric priors for vectors of survival functions [PDF]

open access: yes
The paper proposes a new nonparametric prior for two-dimensional vectors of survival functions (S1,S2). The definition we introduce is based on the notion of Lévy copula and it will be used to model, in a nonparametric Bayesian framework, two-sample ...
Antonio Lijoi, Ilenia Epifani
core   +2 more sources

A Matter of Life and Death: Innovation and Firm Survival [PDF]

open access: yes
This paper examines the effects of innovation on the survival of manufacturing firms in the Netherlands. The demographics of firms according to their innovative performance and type of innovation are traced by using the Business Register population of ...
Elena Cefis, Orietta Marsili
core  

Hazard regression model and cure rate model in colon cancer relative survival trends: are they telling the same story?

open access: yes, 2008
Hazard regression models and cure rate models can be advantageously used in cancer relative survival analysis. We explored the advantages and limits of these two models in colon cancer and focused on the prognostic impact of the year of diagnosis on ...
Launoy, G.   +12 more
core   +1 more source

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