Results 171 to 180 of about 1,834,040 (263)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Authors reply in response to a letter on "impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a multicenter retrospective study". [PDF]

Ann Intensive Care
Rozenblat D, Dépret F, Lafaurie M.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A retrospective evaluation of bone graft success, implant survival rate and marginal bone loss. [PDF]

Bioinformation
Kaira LS, Srivastava V, Mazumdar S, Mudgal I, Singh K, Prajapati A, Patel M.   +6 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

High-rise syndrome in cats (part 2): injury patterns and survival rate. [PDF]

J Feline Med Surg
Candela Andrade M, Slunsky P, Nerlich A, Aguilera-Rojas M, Brunnberg L.   +4 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Predicting fibroblast activation protein overexpression in the overall survival rate of cancer patients: a systematic review and meta-analysis. [PDF]

Syst Rev
Janani M, Poorkhani A, Sharifiandavaei M, Akbari Z, Pourkhalili K, Golfiroozi S, Amiriani T, Tahmasebifar A, Ahmadi F, Jorjanisorkhankalateh Y, Roudbaraki M, Khori V, Alizadeh AM.   +12 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Soft-Tissue Sarcomas-A Correlation Among Tumor Margin Infiltration, Immunological Markers, and Survival Rate. [PDF]

Int J Mol Sci
Șerban B, Cursaru A, Iordache S, Costache M, Cretu B, Dumitru A, Cirstoiu C.   +6 more
europepmc   +1 more source