Results 31 to 40 of about 212,057 (262)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Rate of Decline of FEV1 as a Biomarker of Survival?

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2021
No abstract ...
Alberto Papi   +2 more
openaire   +3 more sources

A novel robust multi-objective evolutionary optimization algorithm based on surviving rate

open access: yesComplex & Intelligent Systems
Multi-objective evolutionary optimization is widely utilized in industrial design. Despite the success of multi-objective evolutionary optimization algorithms in addressing complex optimization problems, research focusing on input disturbances remains ...
Wenxiang Jiang   +3 more
doaj   +1 more source

Scarring and selection effects on children surviving elevated rates of postneonatal mortality in sub-Saharan Africa

open access: yesSSM: Population Health, 2022
Infants in sub-Saharan Africa face adversity: Infections and undernutrition are major causes of infant deaths and can cause physiological damage with long-lasting adverse scarring effects on the human development of the survivors, for example, in terms ...
Omar Karlsson
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

A New Survival Model: Estimation and Analysis of Failure Data [PDF]

open access: yesThe Egyptian Statistical Journal, 1989
In this work we will introduce a new statistical model for surviving distributions which has an increasing failure rate. The proposed statistical model has one or two parameters and these parameters will be estimated using the method of moments and the ...
Shalaby O.A., Al-Yousef M.H
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Hemolysis, elevated liver enzymes, and low platelet syndrome: Outcomes for patients admitted to intensive care at a tertiary referral hospital

open access: yesHypertension in Pregnancy, 2017
Purpose: The aim was to assess outcomes for pregnancies in which hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome develops and the patient requires transfer for critical care.
Ender Gedik   +5 more
doaj   +1 more source

A 12 Years Neonatal Mortality Rate and Its Predictors in Eastern Ethiopia

open access: yesGlobal Pediatric Health, 2021
Introduction . Surviving and thriving of newborn is essential to ending extreme poverty. However, the surviving and thriving of new born is depends on where neonates are born.
Merga Dheresa, Gamachis Daraje
doaj   +1 more source

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