Results 331 to 340 of about 6,323,337 (377)

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

A genome-wide association study integrated with single-cell and bulk profiles uncovers susceptibility genes for nasopharyngeal carcinoma involved in tumorigenesis via regulation of T cells. [PDF]

Genome Biol
Wang TM, Zhang WL, Xie JR, He YQ, Tang M, Xue WQ, Yang DW, Deng CM, Diao H, Mai ZM, Xiao RW, Liao Y, Li DH, Wu YX, Jiang CT, Zhang JB, Chen XY, Du Y, Tang CL, Jia WH, Zhou T, Li XZ, Zhang PF, Zheng XH, Zhang SD, Hu YZ, Cai Y, Zheng Y, Zhang Z, Jin G, Chen W, Mai HQ, Sun Y, Hu Z, Liu J, Guan XY, Bai F, Bei J, Ma J, Zeng M, Lung ML, Adami HO, Ye W, Lam TH, Shen H, Jia WH.   +45 more
europepmc   +1 more source

Gastric cancer susceptibility genes

World Chinese Journal of Digestology, 2014
openaire   +1 more source

A cross-tissue transcriptome-wide association study identifies new susceptibility genes for benign prostatic hyperplasia. [PDF]

Sci Rep
Wang L, Chen SY, Yang JW, Wang KY, Li KP, Wan S, Li XR, Yang L.   +7 more
europepmc   +1 more source

Novel susceptibility genes and biomarkers for obstructive sleep apnea: insights from genetic and inflammatory proteins. [PDF]

Sleep
Zhao Y, Jiang Y, Wang Y, Zhang H, Zhu J, Jiang X, Shen B, Chen Y, Li D, Pan Y, Han F, Zhang L.   +11 more
europepmc   +1 more source

Author Correction: Trans-ancestry transcriptome-wide association and functional studies to uncover novel susceptibility genes and therapeutic targets for colorectal cancer. [PDF]

NPJ Precis Oncol
Wang L, Hu L, Sun J, Zhao J, Zhou S, Liu L, Yu W, Hu Y, Zhou D, Meng X, Yuan Z, Zhang H, Farrington S, Timofeeva M, Ding K, Little J, Dunlop M, Theodoratou E, Li X.   +18 more
europepmc   +1 more source

Unveiling novel susceptibility genes and drug targets for basal cell carcinoma by a cross-tissue transcriptome-wide association study. [PDF]

Discov Oncol
Sun H, Li L, Xin X, Yan J, Huang T.
europepmc   +1 more source

Characterization of the epidemiology, susceptibility genes and clinical features of viral infections among children with inborn immune errors: a retrospective study. [PDF]

Virol J
Zhang H, Wang W, Zhou Q, Hou J, Ying W, Hui X, Sun J, Liu L, Liu L, Wang C, Zhang H, Sun B, Wang X.   +12 more
europepmc   +1 more source