Ultrashort Echo Time Quantitative Susceptibility Source Separation in Musculoskeletal System: A Feasibility Study [PDF]
Journal of ImagingThis study aims to demonstrate the feasibility of ultrashort echo time (UTE)-based susceptibility source separation for musculoskeletal (MSK) imaging, enabling discrimination between diamagnetic and paramagnetic tissue components, with a particular focus
Sam Sedaghat +8 more
doaj +8 more sources
Association of iron deposition in MS lesion with remyelination capacity using susceptibility source separation MRI [PDF]
NeuroImage: ClinicalObjectives: Susceptibility source-separation (χ-separation) MRI provides in-vivo proxy of myelin (diamagnetic susceptibility, χdia) and iron concentrations (paramagnetic susceptibility, χpara) in the central nervous system, potentially uncovering myelin-
Hyeong-Geol Shin +10 more
doaj +8 more sources
Magnetic Susceptibility Source Separation Solely from Gradient Echo Data: Histological Validation [PDF]
Tomography, 2022 Quantitative susceptibility mapping (QSM) facilitates mapping of the bulk magnetic susceptibility of tissue from the phase of complex gradient echo (GRE) MRI data.
Alexey V. Dimov +7 more
doaj +6 more sources
NeuroImageTo separate the contributions of paramagnetic and diamagnetic sources within a voxel, a magnetic susceptibility source separation method based solely on gradient-echo data has been developed. To measure the opposing susceptibility sources more accurately,
Hirohito Kan +5 more
doaj +7 more sources
χ-separation: Magnetic susceptibility source separation toward iron and myelin mapping in the brain [PDF]
NeuroImage, 2021 Obtaining a histological fingerprint from the in-vivo brain has been a long-standing target of magnetic resonance imaging (MRI). In particular, non-invasive imaging of iron and myelin, which are involved in normal brain functions and are ...
Hyeong-Geol Shin +12 more
doaj +5 more sources
Thalamic quantitative susceptibility mapping and susceptibility source separation: a critical narrative review of evidence and interpretation [PDF]
Frontiers in NeurologyQuantitative susceptibility mapping (QSM) measures net tissue magnetic susceptibility, which can conceal coexisting contributions of opposite sign. This is relevant to the thalamus, where nuclei differ in cellular composition, myelinated fibers, and ...
Sadegh Ghaderi +13 more
doaj +3 more sources
NeuroImage, 2023 The brain tissue phase contrast in MRI sequences reflects the spatial distributions of multiple substances, such as iron, myelin, calcium, and proteins. These substances with paramagnetic and diamagnetic susceptibilities often colocalize in one voxel in ...
Zhenghao Li +8 more
doaj +6 more sources
In-vivo iron mapping in patients with Parkinson’s disease using deep learning-based susceptibility source separation MRI [PDF]
npj Parkinson's DiseaseParkinson’s disease (PD) involves pathological iron accumulation, yet MRI metrics, such as R2* or magnetic susceptibility (χ), lack mechanistic specificity because they convolve paramagnetic and diamagnetic sources. We applied an AI-assisted χ-separation
Hyeong-Geol Shin +7 more
doaj +4 more sources
MRI Quantification of Liver Fibrosis Using Diamagnetic Susceptibility: An Ex Vivo Validation Study [PDF]
TomographyBackground/Objectives: Liver fibrosis, if left untreated, can lead to cirrhosis and cancer. The current standard liver biopsy for fibrosis staging is invasive and prone to risks of complication.
Chao Li +10 more
doaj +2 more sources
NeuroImage, 2023 A sensitive and accurate imaging technique capable of tracking the disease progression of Alzheimer's Disease (AD) driven amnestic dementia would be beneficial.
Maruf Ahmed +6 more
doaj +3 more sources