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ISMRM Annual Meeting, 2023
Most multiple sclerosis (MS) white matter lesions (WMLs) appears hyperintense in quantitative susceptibility mapping (QSM). In the present study, we investigated the comparative contribution of myelin loss and iron deposit to QSM hyperintensity using a susceptibility source separation algorithm disentangling QSM- positive and QSM-negative ...
Reza Rahmanzadeh +12 more
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Most multiple sclerosis (MS) white matter lesions (WMLs) appears hyperintense in quantitative susceptibility mapping (QSM). In the present study, we investigated the comparative contribution of myelin loss and iron deposit to QSM hyperintensity using a susceptibility source separation algorithm disentangling QSM- positive and QSM-negative ...
Reza Rahmanzadeh +12 more
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On-scanner Reconstruction for Susceptibility Source Separation
ISMRM Annual MeetingMotivation: Susceptibility source separation provides valuable quantification of iron and myelin but currently requires offline analysis. Enabling an on-scanner fast and automated reconstruction would enable wider adoption. Goal(s): To implement and validate an inline reconstruction for susceptibility source separation on scanners.
Nashwan Naji +6 more
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ISMRM Annual Meeting, 2023
The visualization and characterization of cortical MS lesions is challenging on conventional MRI. In the present study, we used a susceptibility source separation algorithm to divide the positive and negative susceptibility of quantitative susceptibility mapping (QSM) MRI, so that we could disentangle signal alterations due to myelin loss or iron ...
Jannis Müller +13 more
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The visualization and characterization of cortical MS lesions is challenging on conventional MRI. In the present study, we used a susceptibility source separation algorithm to divide the positive and negative susceptibility of quantitative susceptibility mapping (QSM) MRI, so that we could disentangle signal alterations due to myelin loss or iron ...
Jannis Müller +13 more
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ISMRM Annual Meeting
Motivation: Magnetic susceptibility source separation has potential for characterizing pathological tissue changes in disease. However, existing source separation methods assume isotropic susceptibility, ignoring anisotropy in white matter. Goal(s): To develop a method for anisotropic susceptibility source separation for better susceptibility tensor ...
Zhenghan Fang +6 more
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Motivation: Magnetic susceptibility source separation has potential for characterizing pathological tissue changes in disease. However, existing source separation methods assume isotropic susceptibility, ignoring anisotropy in white matter. Goal(s): To develop a method for anisotropic susceptibility source separation for better susceptibility tensor ...
Zhenghan Fang +6 more
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An improved sub-voxel QSM for susceptibility source separation
ISMRM Annual MeetingConventional quantitative susceptibility mapping (QSM) reconstruction methods only provide voxel-averaged susceptibility value. We proposed a comprehensive complex signal model that describes the relationship between the 3D GRE signal and the contributions of opposing susceptibility to the frequency shift and $$$R_2^*$$$ relaxation.
Zhenghao Li, Ruimin Feng, Hongjiang Wei
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ISMRM Annual Meeting
Motivation: Tissue magnetic susceptibility originates from multiple sources, including paramagnetic iron and diamagnetic myelin. Current techniques for source separation in susceptibility imaging assume the susceptibility to be isotropic and require time-consuming R2 measurements.
Zhenghan Fang +6 more
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Motivation: Tissue magnetic susceptibility originates from multiple sources, including paramagnetic iron and diamagnetic myelin. Current techniques for source separation in susceptibility imaging assume the susceptibility to be isotropic and require time-consuming R2 measurements.
Zhenghan Fang +6 more
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ISMRM Annual Meeting
The in-vivo imaging of iron and myelin concentrations of the motor cortex in amyotrophic lateral sclerosis (ALS) patients has significance in advancing knowledge about the degeneration progress of the disease. Here, we explored the feasibility of applying 𝜒-separation to ALS patients in-vivo at 7T.
Jiye Kim +11 more
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The in-vivo imaging of iron and myelin concentrations of the motor cortex in amyotrophic lateral sclerosis (ALS) patients has significance in advancing knowledge about the degeneration progress of the disease. Here, we explored the feasibility of applying 𝜒-separation to ALS patients in-vivo at 7T.
Jiye Kim +11 more
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American Journal of Neuroradiology
Congenital heart disease (CHD) is a significant risk factor for neurodevelopmental impairments, yet the underlying brain alterations in the early postnatal period remain poorly understood. This prospective study measured regional magnetic susceptibilities to characterize tissue composition changes in the brain of newborns with CHD.A total of 51 ...
MinJung, Jang +14 more
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Congenital heart disease (CHD) is a significant risk factor for neurodevelopmental impairments, yet the underlying brain alterations in the early postnatal period remain poorly understood. This prospective study measured regional magnetic susceptibilities to characterize tissue composition changes in the brain of newborns with CHD.A total of 51 ...
MinJung, Jang +14 more
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High resolution sub-voxel magnetic susceptibility source separation of pigeon head at 14.1T
ISMRM Annual MeetingMotivation: The precise mechanisms through which pigeons detect and utilize the Earth's magnetic field for orientation and navigation remain to be fully explored. The χ-separation, which is capable of disentangling the sub-voxel contributions of paramagnetic and diamagnetic susceptibility, is utilized to provide novel insights into this physiological ...
Hongyi Yang +6 more
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Canadian Journal of Forest Research, 1988
Seven lodgepole pine (Pinusconforta Dougl.) provenances collected along an east–west transect from the Cypress Hills, Saskatchewan, to Vancouver, British Columbia, were inoculated as 1-year-old seedlings with one coastal and three British Columbia interior western gall rust (Endocronartiumharknessii (J.P. Moore) Y.
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Seven lodgepole pine (Pinusconforta Dougl.) provenances collected along an east–west transect from the Cypress Hills, Saskatchewan, to Vancouver, British Columbia, were inoculated as 1-year-old seedlings with one coastal and three British Columbia interior western gall rust (Endocronartiumharknessii (J.P. Moore) Y.
openaire +1 more source