Results 51 to 60 of about 1,219,436 (263)

Biomphalaria alexandrina snails as immunogens against Schistosoma mansoni infection in mice

open access: yesMemorias do Instituto Oswaldo Cruz, 2010
Despite effective chemotherapy, schistosomiasis remains the second largest public health problem in the developing world. Currently, vaccination is the new strategy for schistosomiasis control.
Manal A Hamed   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Malus Hosts–Erwinia amylovora Interactions: Strain Pathogenicity and Resistance Mechanisms

open access: yesFrontiers in Plant Science, 2019
The bacterium, Erwinia amylovora, deposits effector proteins such as AvrRpt2EA into hosts through the type III secretion pathogenicity island to cause fire blight in susceptible Malus genotypes.
Ofere Francis Emeriewen   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

In vitro and In vivo Management of Bacterial Blight (Xanthomonas axonopodis pv. cyamopsidis) of Clusterbean

open access: yesJournal of Pure and Applied Microbiology
Bacterial Blight of clusterbean(BLB), which is brought on by Xanthomonas axonopodis pv. cyamopsis, is a significant disease that causes severe infestation, resulting in losses of 58-68% of seed production.
Prahlad   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

COMPARATIVE STUDY OF THE MOTHER SPOROCYST OF SCHISTOSOMA MANSONI IN THE SUSCEPTIBLE AND RESISTANT SNAILS OF BIOMPHALARIA GLABRATA [PDF]

open access: yesPakistan Veterinary Journal, 2007
The comparative studies of the susceptible and resistant snails of Biomphalaria glabrata mass exposed to miracidia of Schistosoma mansoni were conducted from 1 to10 days post-exposure (DPE). Histological sections of 50 susceptible and 50 resistant snails
I. B. KALHORO, S. JALALI1 AND S. A. SHAMI
doaj  

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