Results 141 to 150 of about 278,026 (305)
, 1964 Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about an Indian man who was questioned about the rape of a young blind ...
WBAP-TV (Television station : Fort Worth, Tex.)
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
, 1961 Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news ...
WBAP-TV (Television station : Fort Worth, Tex.)
core
[News Clip: Negro murder suspect]
, 1959 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a Dallas murder ...
WBAP-TV (Television station : Fort Worth, Tex.)
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 1959 Script from the WBAP-TV/NBC station in Fort Worth, Texas, covering a news story about a suspect, in the June 10th murder of Ft. Worth couple Mr. and Mrs. Vernon Stanley. The suspect was said to be found hiding behind a tree at the couples home.
WBAP-TV (Television station : Fort Worth, Tex.)
core
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Imaging of hip trauma - occult, suspect and concomitant fractures
, 2016 Background: Between one and nine percent of all hip fractures are occult or suspect and further examinations with computed tomography (CT) and/or magnetic resonance imaging (MRI) are vital for further handling.
Collin, David
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source