Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Reply : Primary suspect drugs of cataracts in pediatric patients: FDA adverse events reporting database analysis. [PDF]
Khan SM +3 more
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Hepatocellular carcinoma in a child with hereditary tyrosinemia type I despite early NTBC therapy: When should we suspect it? [PDF]
Ouassou KL, Abilkassem R.
europepmc +1 more source
High-Throughput Suspect Screening Reveals Widespread Pesticide Exposure in Early Childhood. [PDF]
Zhao H +11 more
europepmc +1 more source
The Clinical Significance of the Early Screening of Keratoconus and Its Impact on Maintaining Quality of Life. [PDF]
Ismaili M.
europepmc +1 more source
Lessons from an investigation of an autochthonous chikungunya outbreak in Bergerac, mainland France, June to October 2025. [PDF]
Creuse R +10 more
europepmc +1 more source
Drug-Induced Intestinal Angioedema: A Disproportionality Analysis Using the United States Food and Drug Administration Adverse Event Reporting System Database and Literature Review. [PDF]
Bharathi Rajaduraivelpandian P +2 more
europepmc +1 more source

