Results 101 to 110 of about 1,178,909 (237)
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Efecto de la ceniza volcánica sobre la supervivencia de ortópteros en la Patagonia [PDF]
, 2015 El objetivo de este trabajo fue evaluar la toxicidad de las cenizas volcánicas del volcán Puyehue-cordón Caulle en la supervivencia de dos especies de Orthoptera: la tucura Dichroplus vittigerum y la langosta verde Brugilis sp.
Amadio, María Emilia +5 more
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
El derecho a la libertad de cátedra en la España del siglo xix: la "tercera cuestión universitaria" [PDF]
, 2002 SUMARIO:1. Introducción.-2. El antecedente remoto: la primera cuestión universitaria.-3. El antecedente próximo: la segunda cuestión universitaria.-4. Otros antecedentes de la tercera cuestión universitaria.-5. La libertad de cátedra y la persecución de
Lima Torrado, Jesús
core +2 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
LEY GENERAL TRIBUTARIA.SUSPENSIÓN . REFERENCIA: R.G. 656/03. FECHA DE LA RESOLUCION: 11/9/03
Crónica Tributaria, 2004 Es procedente la providencia de apremio sobre una sanción administrativa, que no puede considerarse cautelarmente suspendida, por estar pendiente de resolución por el Tribunal Supremo un recurso de casación para la unificación de doctrina.
AA.VV
doaj
Fiesta máxima, condiciones mínimas [PDF]
, 2018 La siguiente investigación indaga sobre el conflicto laboral de los artistas que participaron en la Fiesta Nacional de la Vendimia del año 2011 "Los Rostros de Vendimia", conflicto que desencadenó en la suspensión de las dos repeticiones del ...
Alsina, Verónica, Garay, Tamara
core
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source