Results 51 to 60 of about 126,874 (286)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Síntese e caracterização de beads acrílicos preparados por polimerização em suspensão visando aplicação como excipiente farmacêutico para compressão direta

open access: yesQuímica Nova, 2012
One of the difficulties reported for the suspension polymerization is control the size and granulometry of beads. The purpose of this work was to evaluate the use of cellulose nanowhiskers and mesoporous silica as stabilizers to reduce the size and the ...
Janaina Cecília Oliveira Villanova   +4 more
doaj   +1 more source

Antimicrobial nano-silver non-woven polyethylene terephthalate fabric via an atmospheric pressure plasma deposition process [PDF]

open access: yes, 2015
An antimicrobial nano-silver non-woven polyethylene terephthalate (PET) fabric has been prepared in a three step process. The fabrics were first pretreated by depositing a layer of organosilicon thin film using an atmospheric pressure plasma system, then
Aziz, Gaelle   +7 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Optimization of Synthesis of Expandable Polystyrene by Multi-Stage Initiator Dosing [PDF]

open access: yesIranian Journal of Chemical Engineering, 2016
Suspension polymerization process is commonly used to produce expandable polystyrene. In the conventional method for producing this polymer, two different initiators are added to the process at two different temperature levels.
F. derakhshanfard   +3 more
doaj  

Continuous Function Approximation for Dispersed Phase Distribution in Suspension Polymerization

open access: yesChemical Engineering Transactions, 2012
Polymers are nowadays used in a multitude of applications, many of the latter being in close relationship with the polymer molecular mass distribution (PMMD), which could be affected by the way the polymer was obtained: bulk, solution, emulsion or ...
G.R. Palau, R. Isopescu, V. Lavric
doaj   +1 more source

Trispyrazolylborate Ligands Supported on Vinyl Addition Polynorbornenes and Their Copper Derivatives as Recyclable Catalysts [PDF]

open access: yes, 2019
Polynorbornenes prepared by vinyl addition poly- merization and bearing pendant alkenyl groups serve as skeletons to support trispyrazolylborate ligands (Tpx) built at those alkenyl sites.
Albéniz Jiménez, Ana Carmen   +6 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Droplets Size Distribution Analysis in Suspension Polymerization of Methyl Methacrylate.

open access: yesChemical Engineering Transactions, 2010
preview not available - see full-text PDF article.
R.D. Isopescu   +4 more
doaj   +1 more source

Tomato EF-Tsmt, a functional mitochondrial translation elongation factor from higher plants [PDF]

open access: yes, 2003
Ethylene-induced ripening in tomato (Lycopersicon esculentum) resulted in the accumulation of a transcript designated LeEF-Tsmt that encodes a protein with significant homology to bacterial Ts translational elongation factor (EF-Ts).
Benichou, Mohamed   +10 more
core   +2 more sources

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