Results 111 to 120 of about 21,632 (263)

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Research on Multi-objective Topology Optimization of Vehicle Suspension Control Arm [PDF]

, 2017
Zhang Zhi-fei
openalex   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Effects of Mechanical and Electrical Topologies on Piezoelectric Stacked Energy Harvesting in Vehicle Suspensions [PDF]

Yang Li, Ruoyu Wang, Zhao Wan, Ming Chen, Guijie Liang   +4 more
openalex   +1 more source

An application of the Bott suspension map to the topology ofEIV [PDF]

, 1966
Lawrence Conlon
openalex   +1 more source

Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks

Advanced Science, EarlyView.
This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen, Qing Zhao, Wentao Fu, Weixian Chen, Xiaoqian Zhang, Gaiying Ye, Qinglei Meng, Liyuan Shao, Qian Ma, Lin Zhao, Ying Zhao, Weihua Guo   +11 more
wiley   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Automated Design Methodology for Electromagnetic Energy Harvesters. [PDF]

Sensors (Basel)
Leistritz B, Herzog L.
europepmc   +1 more source

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

Advanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin, Jiale Sun, Yuqing Mao, Yuhao Tang, Fuan Wang, Zhihong Liu, Jing Wang   +6 more
wiley   +1 more source

Quantum-topological meta-learning for tire-road contact stability and multi-modal road prediction in autonomous driving. [PDF]

PLoS One
Wang N.
europepmc   +1 more source