Results 221 to 230 of about 6,301,297 (333)
Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study
Arthritis Care &Research, Accepted Article.Objective
This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods
This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel +19 morewiley +1 more sourcePolicy recommendations and cost implications for a more sustainable framework for European human biomonitoring surveys
, 2014 Anke Joas, Lisbeth E. Knudsen, Marike Kolossa‐Gehring, Ovnair Sepai, Ludwine Casteleyn, Greet Schoeters, J. Angerer, Argelia Castaño, Dominique Aerts, Pierre Biot, Milena Horvat, Louis Bloemen, M. Fátima Reis, Ioana-Rodica Lupsa, Andromachi Katsonouri, Milena Černá, Marika Berglund, Pierre Crettaz, Péter Rudnai, Katarína Halzlová, Maurice Mulcahy, Arno C. Gutleb, Marc Fischer, Georg Becher, Nadine Fréry, Génon K. Jensen, Lisette van Vliet, Holger M. Koch, Elly Den Hond, Ulrike Fiddicke, Marta Esteban, Karen Exley, Gerda Schwedler, Margarete Seiwert, Danuta Ligocka, Philipp Hohenblum, Soterios Α. Kyrtopoulos, Maria Botsivali, Elena DeFelip, Claude Guillou, Fabiano Reniero, Regina Gražulevičienė, Toomas Veidebaum, Thit Aarøe Mørck, Jeanette K.S. Nielsen, Janne Jensen, Teresa C. Rivas, Jinny Sánchez, Gudrun Koppen, Roel Smolders, Szilvia Középesy, Adamos Hadjipanayis, Andrea Krsková, Russell Mannion, M. Jakubowski, J. Aleksandra Fucic, José Pereira Miguel, Anca Elena Gurzău, Michal Jajcaj, Darja Mazej, Janja Snoj Tratnik, Andrea Lehmann, Kristin Larsson, Birgit Dumez, Reinhard Joas +64 moreopenalex +2 more sourcesBeyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis
Arthritis Care &Research, EarlyView.Persistent pain remains a major challenge in inflammatory arthritis, even when joint inflammation is well controlled. Pain and associated symptoms such as fatigue cannot be explained by peripheral inflammation alone but reflect altered central pain processing. These changes may arise through “top‐down” mechanisms, reflecting pre‐existing dysfunction in Eoin M. Kelleher, Rosario Meouchi, Anushka Irani +2 morewiley +1 more sourceRRP9 Promotes Esophageal Squamous Cell Carcinoma Progression through E2F1 Transcriptional Regulation of CDK1
Advanced Biology, EarlyView.The study reveals that RRP9 is abnormally highly expressed in ESCC tissues and is closely associated with poor prognosis in patients. Furthermore, it is found that RRP9 promotes ESCC progression through enhancing the E2F1‐mediated transcriptional regulation of CDK1.Gang He, Yilong Wan, Yanbo Zhu, Bo Peng, Shengxiang Shao, Xinyi Zou, Zhenyu Han, Jiaxi Li, Sheng Ju, Xin Tong, Jun Zhao, Hansi Liang, Liuqing Zhang, Jiashi Xiong, Dong Jiang +14 morewiley +1 more sourceHollow silica capsules for amphiphilic transport and sustained delivery of antibiotic and anticancer drugs
, 2018 Isabel Gessner, Eva Krakor, Anna Jurewicz, Veronika Wulff, Lasse Kling, Silke Christiansen, Nicolas Brodusch, Raynald Gauvin, Laura Wortmann, Martina Wolke, Georg Plum, Astrid Schauß, John Krautwurst, Uwe Ruschewitz, Shaista Ilyas, Sanjay Mathur +15 moreopenalex +2 more sourcesLung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome
Advanced Biology, EarlyView.This study aims to evaluate the efficacy of primed mesenchymal stem cells (pMSCs) as an alternative treatment for Acute Respiratory Distress Syndrome (ARDS), based on a novel lung microphysiological system (MPS) to test the efficacy of pMSCs over the standard treatment, Dexamethasone.Bokyong Kim, So‐Hui Kim, Jieun Kim, Eun‐Young Eo, Hyung‐Jun Kim, Jae Ho Lee, Choon‐Taek Lee, Taeho Kong, Su Kyoung Seo, Seunghee Lee, Jeongbin Park, Young‐Jae Cho +11 morewiley +1 more source
