Results 41 to 50 of about 2,796,465 (333)

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Unlike rolling stones: not every Myrmecina species actively rolls away from danger (Hymenoptera, Formicidae)

The European Zoological Journal, 2022
Actively rolling away is a very rare escape strategy in the animal kingdom, which to date has only been documented in a few arthropod and one vertebrate species.
D. Giannetti, E. Schifani, C. Castracani, F. A. Spotti, A. Mori, D. A. Grasso   +5 more
doaj   +1 more source

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

Molecular Oncology, EarlyView.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park, Keeok Haam, Haejeong Heo, Doyeong Kim, Min‐Ju Kim, Hyo‐Jung Jung, Seongwon Cha, Mirang Kim, Haeseung Lee   +8 more
wiley   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Sustainability in Debate Sustentabilidade em Debate

Sustentabilidade em Debate, 2012
Full Journal.
Sustainability in Debate
doaj  

WGV: An Australian Urban Precinct Case Study to Demonstrate the 1.5 °C Agenda Including Multiple SDGs

Urban Planning, 2018
The WGV project is an infill residential development in a middle suburb of Perth, Western Australia. Its urban planning innovation is in its attempt to demonstrate net zero carbon as well as other sustainability goals set by urban planning processes such
Jason Wiktorowicz, Tanya Babaeff, Jessica Breadsell, Josh Byrne, James Eggleston, Peter Newman   +5 more
doaj   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Linking concepts of change and ecosystem services research: A systematic review

Change and Adaptation in Socio-Ecological Systems, 2018
Transformation, transition and regime shift are increasingly applied concepts in the academic literature to describe changes in society and the environment.
Rau Anna-Lena, Bickel Manuel W., Rathgens Julius, Schroth Thilo N., Weiser Annika, Hilser Stefan, Jenkins Shona, McCrory Gavin, Pfefferle Nicole, Roitsch Dennis, Stålhammar Sanna, Villada Danna, Wamsler Christine, Krause Torsten, von Wehrden Henrik   +14 more
doaj   +1 more source

Explainable Natural Language Processing for Corporate Sustainability Analysis [PDF]

Information Fusion.115 (2025) 102726
Sustainability commonly refers to entities, such as individuals, companies, and institutions, having a non-detrimental (or even positive) impact on the environment, society, and the economy. With sustainability becoming a synonym of acceptable and legitimate behaviour, it is being increasingly demanded and regulated.
arxiv   +1 more source

Sustainability Competencies and Skills in Software Engineering: An Industry Perspective [PDF]

arXiv, 2023
Achieving the UN Sustainable Development Goals (SDGs) demands adequate levels of awareness and actions to address sustainability challenges. Software systems will play an important role in moving towards these targets. Sustainability skills are necessary to support the development of software systems and to provide sustainable IT-supported services for
arxiv