Results 71 to 80 of about 176,787 (255)

Phosphorus-activated carboxyl small molecule positive electrode for high specific capacity and long-life iron-organic batteries

Nature Communications
Iron-ion batteries represent a compelling energy storage solution due to the cost-effectiveness, suitable redox potential, and high capacity of Fe negative electrodes.
Yehui Zhang, Qi Huang, Pingxuan Liu, Yaokang Lv, Ziyang Song, Lihua Gan, Mingxian Liu   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Opportunity cost estimates for spatial conservation prioritisation across terrestrial Europe

Scientific Data
Opportunity costs of conservation represent the foregone economic benefits from using land for nature conservation rather than alternative activities. Considering opportunity costs therefore helps in identifying cost-effective solutions in conservation ...
Douglas Spencer, Alexandra Marques, Clara J. Veerkamp, Martijn van der Marel, Peter Verburg, Moreno Di Marco, Martin Jung, Heini Kujala, Louise O’Connor, Piero Visconti, Aafke M. Schipper   +10 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NH4 +-Modulated Cathodic Interfacial Spatial Charge Redistribution for High-Performance Dual-Ion Capacitors

Nano-Micro Letters
Highlights Hierarchical Zn2+/NH4 + solvation structure induces cathodic interfacial Helmholtz plane reconfiguration to enhance spatial charge density and capacity storage.
Yumin Chen, Ziyang Song, Yaokang Lv, Lihua Gan, Mingxian Liu   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

NEGOTIATING SUSTAINABILITY WITH SUSTAINABILITY ASSESSMENT

, 2015
Welcome to the book of blogs, a collection of diverse works from researchers across the globe who all have something important to say about the way in which our world is changing and how we can strive towards a more sustainable future. This book emerged from an International Social Science Council (ISSC) meeting in November 2014 of early career ...
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Restructuring and Hydrogen Evolution on Sub-Nanosized Pd_xB_y Clusters

Molecules
As a Pt-group element, Pd has been regarded as one of the alternatives to Pt-based catalysts for the hydrogen evolution reaction (HER). Herein, we performed density functional theory (DFT) computations to explore the most stable structures of PdxBy (x ...
De Zhang, Ruijing Wang, Sijia Luo, Guangfeng Wei   +3 more
doaj   +1 more source