Results 121 to 130 of about 9,540,642 (235)
Sustainability Report and Company Performance: The Geopolitical Impact in Indonesia
Recent global crises, such as the 2022 Russia-Ukraine conflict and heightened global temperatures, have emphasized the need for robust sustainability practices amid volatile geopolitical environments.
Sri Rahayu +4 more
doaj +1 more source
Pursuing environmental sustainability [PDF]
This report describes findings from research that was conducted with organisations that have put environmental integrity or ecological sustainability at the core of their mission.
Bebbington, Jan, Barter, Nicholas J.
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
High Volume Hydraulic Fracturing In Michigan Integrated Assessment Final Report [PDF]
This report is part of the Hydraulic Fracturing in Michigan Integrated Assessment (IA) which has been underway since 2012. The guiding question of the IA is, “What are the best environmental, economic, social, and technological approaches for managing ...
Callewaert, John +8 more
core +1 more source
Introduction/Main Objectives: The increasing demand for sustainability reports encourages companies to be more transparent in disclosing social and environmental impacts, especially for global companies in the era of digital transformation.
Abim Wafirli +3 more
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Kualitas Laporan Keuangan Ditinjau dari Enterprise Risk Management
Financial reports play a crucial role for external parties in monitoring company performance, tracking growth, and evaluating achievements. However, pressure to make reports appealing to prospective investors and stakeholders often leads to financial ...
Fiinaa Maghfirotuzzahro +2 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
UBC Food System : framework for assessing sustainability
The global food system is a huge industry that has a major impact on environmental, social, and economical sustainability. The UBC food system represents a microcosm of the global food system, similarly impacting the sustainability of UBC.
Rommel, Marina +7 more
core
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source

