Results 121 to 130 of about 17,045,549 (317)

Recent trends in sustainability reporting: Literature review and implications for future research

open access: yesEkonomski Vjesnik, 2020
Sustainability reporting has become a topical issue in recent years as it is no longer enough to make claims about the sustainability level of companies, but it is also necessary to demonstrate their sustainability efforts.
Ana Zrnić   +2 more
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

PENGARUH KARAKTERISTIK DEWAN KOMISARIS TERHADAP PENGUNGKAPAN SUSTAINABILITY REPORTING DENGAN UKURAN PERUSAHAAN SEBAGAI VARIABEL MODERASI (Studi Empiris pada Perusahaan Manufaktur yang terdaftar di BEI Tahun 2014- 2015) [PDF]

open access: yes, 2017
This research aims to analyze :(1) the influence of board commissioners characteristics on sustainability reporting (2) the influence of firm size as the moderating variable in relations between board commissioners characteristics and sustainability ...
AISYAH, Wulandari Siti, FUAD, Fuad
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

ACCOUNTING FOR SUSTAINABILITY: WHAT NEXT? A RESEARCH AGENDA [PDF]

open access: yes
This working paper responds to increasing calls for more and different forms of accounting research involvement in accounting for sustainability. It seeks to provide background, clarify the accounting research issues, and suggest research methods.
Cunningham Gary M.   +2 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

PENGARUH KARAKTERISTIK DEWAN KOMISARIS TERHADAP LAPORAN KEBERLANJUTAN [PDF]

open access: yes, 2018
The purpose of this study is to determine the effect of board of commissioner characteristics on the reporting of the sustainability of public companies in Indonesia Stock Exchange (IDX), Indonesia.
CHARIRI, Anis, WULANDARI, Putri
core  

On the effectiveness of private transnational governance regimes - evaluating corporate sustainability reporting according to the Global Reporting Initiative [PDF]

open access: yes, 2015
The increasing involvement of multinational enterprises (MNEs) in global governance has been both applauded for its potential to make governance more effective and criticized for lacking democratic legitimization.
Ashforth   +122 more
core   +3 more sources

Home - About - Disclaimer - Privacy