From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The Association between Sustainability Reporting Disclosure and Stock Price Crash Risk: Moderating Effect of Earnings Quality: An Empirical Study [PDF]
Purpose – The purpose of this article is to investigate the moderating effect of earnings quality on the association between sustainability reporting disclosure and stock price crash risk in Egyptian listed firms.Design/methodology/approach – This study ...
Aml Badr +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Pursuing environmental sustainability [PDF]
This report describes findings from research that was conducted with organisations that have put environmental integrity or ecological sustainability at the core of their mission.
Bebbington, Jan, Barter, Nicholas J.
core +2 more sources
The Effect of Sustainibility Reporting Disclosure and Its Impact on Companies Financial Performance
The purpose of this research was to examine empirically the effect of sustainability reporting disclosure on company performance. Sustainability reporting is a report that measures, discloses and shows the responsibility of the company to internal and ...
Enny Hardi, Chairina Chairina
doaj +1 more source
Measuring and Reporting on Sustainability Performance in the Cement Industry [PDF]
Corporate Social Responsibility (CSR) performance assessment and reporting has drawn a considerable amount of attention. In this context, the Global Reporting Initiative (GRI) has been among the first organizations to develop a framework for ...
Adrian VAIDA, Dan CANDEA
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
ACCA's 'Meet the winners and judges' reporting workshop [PDF]
This document outlines the key points of the reporting workshop held as part of the 2008 ACCA UK Awards for Sustainability Reporting.
Association of Chartered Certified Accountants
core +2 more sources
Corporate sustainability reporting index and baseline data for the cruise industry [PDF]
Sustainability policies and corporate reports demonstrate the impacts cruise companies acknowledge as their responsibility, and the actions put in place to address them.
Bonilla-Priego, MJ +2 more
core +1 more source

