Results 91 to 100 of about 292,782 (296)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Sustainability Science: Towards a Synthesis

, 2020
Keywords: sustainability science; sustainable development; Anthropocene; well-being; inclusive wealth; adaption; sustainability transformations; governance Citation: Clark, William C., and Alicia G. Harley. 2019.
Harley, Alicia, Clark, William
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Software Sustainability: The Modern Tower of Babel [PDF]

, 2014
The aim of this paper is to explore the emerging definitions of software sustainability from the field of software engineering in order to contribute to the question, what is software sustainability?
Rupert R. Ward (455130), Lau, Lydia, Venters, Colin C, Caroline Jay (403849), Holmes, Violeta, Austin, Jim, Griffiths, Michael K., Ward, Rupert, Charlie E. Dibsdale (663698), Jay, Caroline, Dibsdale, Charlie E., Xu, Jie, Jie Xu (34477), Venters, Colin, Griffiths, Michael K, Lydia Lau (455127), Violeta Holmes (455129), Michael K. Griffiths (455128), Colin C. Venters (453572), Jay, Caroline; id_orcid, Dibsdale, Charlie E, Jim Austin (663697)   +21 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Handbook of sustainability science and research

, 2017
This multidisciplinary handbook explores concrete case studies which illustrate how sustainability science and research can contribute to the realization of the goals of the 2030 Agenda for Sustainable Development.

core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Science and sustainability: evaluation of integration of science concepts with global issues

, 2004
Science and Sustainability is an innovative Grade 10 SEPUP course which aims to integrate important concepts of science with the study of global sustainability in a motivating and interactive fashion to address National Science Education Standards.
Ratcliffe, Mary
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source