Results 81 to 90 of about 3,310,090 (304)

Agroecological transitions: What can sustainability transition frameworks teach us? An ontological and empirical analysis

open access: yesEcology and Society, 2018
Transitioning toward more sustainable agricultural development paths requires extensive change and not simply marginal technical adjustments, as suggested by a strong conception of agroecology.
Guillaume Ollivier   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Citizen science and sustainability transitions

open access: yesResearch Policy, 2019
Citizen Science (CS) projects involve members of the general public as active participants in research. While some advocates hope that CS can increase scientific knowledge production ('productivity view'), others emphasize that it may bridge a perceived gap between science and the broader society ('democratization view').
Sauermann, Henry   +10 more
openaire   +5 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Diversity in Central Asia: Culture, transition & entrepreneurship [PDF]

open access: yes, 2009
With the demise of the USSR in 1991, five new countries became independent in Central Asia. This study presents an overview about transition, emergence and nature of entrepreneurship in a world’s region that displays amongst the most important energy ...
Dana, Leo-Paul   +2 more
core  

Advancing Sustainability Through Land-Related Approaches: Insights from NRC (1999) and a Bold Call to Action

open access: yesLand
This paper investigates the critical role of land in advancing sustainability, drawing insights from the landmark report by the U.S. National Research Council, Our Common Journey: A Transition Toward Sustainability (hereafter referred to as NRC (1999 ...
Bing-Bing Zhou   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Work-life balance, organizations and social sustainability: analyzing female telework in Spain

open access: yes, 2020
The concept of work-life balance has recently established itself as a key component on route maps drawn up in the pursuit of social sustainability, both on a local scale, represented by individual organizations, and on a more general one, represented by ...
Tirado Serrano, Francisco Javier   +5 more
core   +1 more source

Enhancing participatory governance in biosphere reserves through co-creation of transdisciplinary and intergenerational knowledge

open access: yesFrontiers in Environmental Science
In the context of the current global climate and biodiversity crisis, urgent action is needed to improve participatory and co-productive governance in territories under sustainability directives, such as biosphere reserves.
Marcelo Leguia-Cruz   +4 more
doaj   +1 more source

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