Results 181 to 190 of about 2,302,279 (319)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Sustainable lives : what will sustainable lifestyles look like? : a provocation

, 2012
In Sustainable Lives, published in 2009, Alan Knight, ex-SDC Commissioner for Business and Sustainable Consumption, outlines ten key principles for determining what a sustainable lifestyle might look like.
Knight, Alan, Sustainable Development Commission   +1 more
core  

Considering sustainability thresholds for BECCS in IPCC and biodiversity assessments

GCB Bioenergy, 2021
Felix Creutzig, Karl‐Heinz Erb, Helmut Haberl, Christian Hof, Carol Hunsberger, Stephanie Roe   +5 more
doaj   +1 more source

Self-control and the sustainable citizen. [PDF]

Appl Psychol Health Well Being
André N, Baumeister R.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Stock take : delivering improvements in existing housing

, 2012
The Sustainable Development Commission was commissioned by the Office of the Deputy Prime Minister to examine the potential for significantly improved resource efficiency in the existing housing stock.
Sustainable Development Commission
core  

Beyond algorithmic trust: human-AI interaction competency strengthens AI-driven financial decision-making and financial resilience. [PDF]

Front Artif Intell
Vijayananth M, Saravanabhavan N.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The response of the Sustainable Development Commission to the ‘Code for sustainable homes’

, 2012
This document is the Sustainable Development Commissions response to inform the 'Code for sustainable homes'.The Government is developing the 'Code for sustainable homes' as a component of its sustainable communities agenda. Key environmental challenges,
Sustainable Development Commission
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source