Results 111 to 120 of about 68,953 (307)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The Effect of Visual Landscape Design on the Emotional and Physiological Responses of Older Adults

Buildings
Landscape quality significantly impacts residents’ well-being through visual perception, particularly among the elderly who exhibit heightened sensitivity to environmental stimuli. Therefore, this study investigates how landscape configurations influence
Yalin Zhang, Menglin Zhang, Xiangxi Li, Keming Hou, Weijun Gao   +4 more
doaj   +1 more source

Exploring biomimicry in agriculture focuses on how insights from natural systems can revolutionize farming practices and enhance food security [PDF]

BIO Web of Conferences
Biomimicry, a design philosophy that is based on the principles of nature, presents a promising solution to the sustainability challenges faced by modern agriculture.
Othmani Nurul Izzati, Wan Mohamad Wan Saiful Nizam, Abdul Hamid Nor Hamizah, Ramlee Noorliyana, Yeo Lee Bak, Hasan Ramly, Ibrahim Ismi Luqman Hamadi, Mustapa Nor Diyana, Mohd Jain Noordin Mohd Azri, Khairuddin Muhammad Rizal, Othmani Iylia Athirah   +10 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Climate-Based Assessment of Radiative Cooling Potential Using Energy Simulation and Atmospheric Indicators

Buildings
Rising global temperatures are driving an urgent need for buildings that consume less energy while maintaining comfort. Cooling demand is surging worldwide, yet conventional air-conditioning remains energy-intensive and carbon-heavy.
Xiaolin Ding, Shanshan Li, Chenxi Hu, Qian Yu, Hiroatsu Fukuda, Weijun Gao   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

The Study of the Relationship between Sustainable Architecture and Vernacular Architecture in the North of Iran

, 2017
This study investigates sustainable architecture and reasons of its usage. Architecture is under influence of a range of socio-economic aspects including but not limited environmental, social, cultural, economical problems and the connection between ...
A. Niki, Mohammadali Vatandoost
semanticscholar   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source