Results 71 to 80 of about 4,166,525 (285)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Sustainable development and UK faith groups : two sides of the same coin? : a survey of UK faith communities’ sustainable development activities and next steps for the future [PDF]

open access: yes, 2012
English language version of 'Datblygu cynaliadwy a grwpiau ffydd y DU : dwy ochr yr un geiniog? : arolwg o weithgareddau datblygu cynaliadwy cymunedau ffydd y DU a’r camau nesaf ar gyfer y dyfodol'.A survey of UK faith communities’ sustainable ...
World Wildlife Fund UK   +1 more
core   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A Study on the Effect of Dynamic Photovoltaic Shading Devices on Energy Consumption and Daylighting of an Office Building

open access: yesBuildings
Photovoltaic shading devices (PVSDs) have the dual function of providing shade and generating electricity, which can reduce building energy consumption and improve indoor daylighting levels.
Yan Jiang   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Sustainable development : the key to tackling health inequalities [PDF]

open access: yes, 2012
In November 2008, Professor Sir Michael Marmot was asked to advise the Secretary of State for Health on the future development of a health inequalities strategy in England post-2010.
Sustainable Development Commission
core   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Effects of Dynamic Increases in Indoor CO2 Concentration on Daytime Sleepiness: An EEG-Based Study

open access: yesBuildings
Elevated indoor carbon dioxide (CO2) concentrations are increasingly recognized as a critical determinant of occupant health and cognitive performance; however, the neurophysiological mechanisms linking CO2 exposure to daytime sleepiness remain a subject
Baiyi Guo   +3 more
doaj   +1 more source

A Modular Timber Construction System for the Sustainable Vertical Extension of Office Buildings

open access: yesDesigns, 2018
Most European cities are facing urban densification issues. In this context, a solution to create usable spaces without additional pressure on land consists in the vertical extension of existing buildings.
Aleksis Dind   +2 more
doaj   +1 more source

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