Results 101 to 110 of about 68,953 (307)

Urban green spaces as a climate adaptation strategy. Case study in Geneva, Switzerland

open access: yesCity and Environment Interactions
In a context marked by the urgency of climate change, dwindling resources, and environmental crisis, concrete action towards ecological transition and climate adaptation is a top priority for urban areas.
Sophie Lufkin, Emmanuel Rey
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Vision and Methodology to Support Sustainable Architecture Through Building Technology in The Digital Era

open access: yesThe Academic Research Community Publication, 2018
The last decades have witnessed countless, progressive, rapid advances in the field of Building Technology, which has a strong impact on construction industry.
Merhan M. Shahda
semanticscholar   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

SUSTAINABLE ARCHITECTURE IMPLEMENTATION OF VERNACULAR MOSQUE IN ACEH, INDONESIA

open access: yesJournal of Islamic Architecture, 2018
As one of the build environment’s products, the existence of the building has a positive and negative contribution towards the surrounding. Along with the emerging of the environmental problems, the architecture sector offers the implementation of the ...
M. Bakri
semanticscholar   +1 more source

Upcycling Prefabricated Building Materials to Develop Pavilions for Community Gardens in Huddersfield, UK

open access: yesProceedings
As average temperatures in the UK continue to rise, and the effects of climate change are felt across communities, the government has revised requirements for urban development pertaining to Biodiversity Net Gain and access to green spaces (under the ...
Yun Gao   +5 more
doaj   +1 more source

A sustainable material for sustainable architecture: wood in parasite architecture

open access: yesCongresso Internacional sobre Patologia e Reabilitação das Construções, 2021
Rinaldi S.   +4 more
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Assessment of Health-Oriented Layout and Perceived Density in High-Density Public Residential Areas: A Case Study of Shenzhen

open access: yesBuildings
Rapid urbanization has intensified public housing development and building density, posing significant challenges to residents’ well-being and urban sustainability. With the population of the Greater Bay Area on the rise, enhancing the spatial quality of
Guangxun Cui   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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