Results 81 to 90 of about 4,416,693 (237)

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Leading by example? : not exactly… : SDC commentary on the Sustainable Development in Government Report 2005 [PDF]

, 2012
Sustainable Development Commission commentary on the 'Sustainable Development in Government Report 2005'.Publisher ...
Sustainable Development Commission
core   +2 more sources

Effects of Dynamic Increases in Indoor CO₂ Concentration on Daytime Sleepiness: An EEG-Based Study

Buildings
Elevated indoor carbon dioxide (CO2) concentrations are increasingly recognized as a critical determinant of occupant health and cognitive performance; however, the neurophysiological mechanisms linking CO2 exposure to daytime sleepiness remain a subject
Baiyi Guo, Wenhao Wang, Baowen Yan, Hongbo Fan   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Mainstreaming sustainable regeneration : a call to action [PDF]

, 2012
Contents: [Part 1]. Main publication – Part 2. Supporting documentsThis report is the culmination of 18 month’s investigation by the Sustainable Development Commission into how neighbourhood regeneration can be made more sustainable.Publisher ...
Sustainable Development Commission
core   +2 more sources

A Systematic Review: Examining the Impacts of Artificial Intelligence

Journal of Artificial Intelligence in Architecture
Since its breakthrough in the mid-20th century, Artificial Intelligence (AI) has held great promises for improving the capacity of urban planning to address complex problems.
David Chow, Catharina Dwi Astuti Depari, Eva Gabriella   +2 more
doaj   +1 more source

A Modular Timber Construction System for the Sustainable Vertical Extension of Office Buildings

Designs, 2018
Most European cities are facing urban densification issues. In this context, a solution to create usable spaces without additional pressure on land consists in the vertical extension of existing buildings.
Aleksis Dind, Sophie Lufkin, Emmanuel Rey   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Sustainable planning and construction for water friendly architecture: lesson from the tsunami

, 2006
The 7th International Conference on Sustainable Environmental Architecture (SENVAR 2006), Hasanuddin University, Indonesia ...
Lau, SSY
core  

Urban green spaces as a climate adaptation strategy. Case study in Geneva, Switzerland

City and Environment Interactions
In a context marked by the urgency of climate change, dwindling resources, and environmental crisis, concrete action towards ecological transition and climate adaptation is a top priority for urban areas.
Sophie Lufkin, Emmanuel Rey
doaj   +1 more source