Results 131 to 140 of about 9,662,874 (348)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Sustainable behaviors and personality moderating the status goal and purchase intention relationship of luxury brands

Journal of Business Economics and Management
Luxury brands are related to two major mechanisms of social adaptation: value-expressive and social-adjustive. Researchers have established that these two functions are likely to influence customer purchase intention.
Jorge Vera-Martínez, Humberto Fuentes, Diana Kolbe   +2 more
doaj   +1 more source

The Iterative Mindset Method: a neuroscientific theoretical approach for sustainable behavior change and weight-loss in digital medicine. [PDF]

NPJ Digit Med, 2023
Bobinet K, Greer SM.
europepmc   +1 more source

Инструменты и коммуникационные стратегии внешней политики в теории международных отношений [PDF]

, 2020
The purpose of this article is to analyze the nature of non-military instruments (economic sanctions, soft power and communication strategies) of foreign policy within the international relations theory, because these tools are becoming increasingly ...
Sedliar, Yulia, Stadnichenko, Olga
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Pension Reform, Retirement and Life-Cycle Unemployment [PDF]

The labor market effects of pension reform stem from retirement behavior and from job search and hours worked of prime age workers. This paper investigates the impact of four often proposed policy measures for sustainable pensions: strengthening the tax ...
Christian Jaag, Christian Keuschnigg, Mirela Keuschnigg   +2 more
core   +3 more sources

Affective and reflective attitudes toward vegetarian food consumption: the effect of goal priming

Frontiers in Nutrition
ObjectivesThe study’s primary goal was to investigate the effect of goal priming on implicit and explicit attitudes toward vegetarian food consumption and food choice behavior within the context of dual-process models that describe sustainable behavior ...
Fabian Daiss, Petra Jansen
doaj   +1 more source

Demand for Vacations /Travel in Protected Areas – Dimension of Tourists’ Ecological Behavior [PDF]

Tourism, in itself, is one of the main users of the environment and, implicitly, an important contributor to its deterioration. Intensification of tourist travel will naturally generate an increase of the negative environmental impacts and, in the long ...
Delia Popescu, Mihaela Pădurean, Remus Hornoiu, Rodica Minciu   +3 more
core  

Explaining tourists´ support for environmental protection [PDF]

, 2016
Any movement towards sustainable tourism is dependent not only upon the industry and other key stakeholders but also the demand side, namely the tourists. Yet, there is a limited literature from the demand point of view. In this area, contributions to an
Campos-Soria, Juan Antonio, García-Pozo, Alejandro, Sanchez-Ollero, Jose Luis   +2 more
core  

Testing a tridimensional model of sustainable behavior: self-care, caring for others, and caring for the planet

Environment, Development and Sustainability, 2021
V. Corral-Verdugo, C. Pato, N. Torres-Soto   +2 more
semanticscholar   +1 more source