Results 141 to 150 of about 9,662,874 (348)
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Can Space Tourism Boost Sustainable Behavior? [PDF]
Mammarella N.
europepmc +1 more source
Understanding the Connections Between Consumer Motivations and Buying Behavior: The Case of the Local Food System Movement [PDF]
Local and organic food systems represent some of the many food sector innovations of the past decade that signal that consumers are increasingly diverse and have heterogeneous preferences that reflect their unique values and preferences (Thilmany, Bond ...
Nurse, Gretchen +2 more
core +1 more source
Green revolution 2.0: a sustainable energy path [PDF]
This repository item contains a single issue of Sustainable Development Insights, a series of short policy essays that began publishing in 2008 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future. The series seeks
Kulatilaka, Nalin
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Critical Portrait of Vocational High School Accounting Teachers Sustainable Awareness in Indonesia
about their actions’ environmental and social impact, Education teaches students to think critically and responsibly towards the surrounding environment.
Sri Sumaryati +3 more
doaj +1 more source
Sustainable Behavior with Respect to Managing E-Wastes: Factors Influencing E-Waste Management among Young Consumers. [PDF]
Garg S, Ahmad A, Madsen DØ, Sohail SS.
europepmc +1 more source
Wonderland, a compact, integrated economic, demographic and environmental model is investigated using methods developed for studying critical phenomena.
Bankes +18 more
core +2 more sources
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source

