Results 51 to 60 of about 159,665 (238)

Determination of the most influential and cost-optimal building characteristics on the energy performance of commercial and industrial buildings [PDF]

open access: yesE3S Web of Conferences, 2019
Unlike other types of buildings, commercial and industrial buildings have been so far “forgotten”. In addition, EPBD requirements are increasingly challenging for this type of buildings.
Breesch Hilde   +2 more
doaj   +1 more source

Towards Sustainable Building Design [PDF]

open access: yesDesign Principles and Practices: An International Journal—Annual Review, 2009
Work recently undertaken at the University of Strathclyde, Department of Architecture, is concerned with the articulation of a management system that might support sustainable design. Aligned with the international standard ISO 14001, a system has been piloted in housing development projects around Glasgow, and offers a supporting framework for the ...
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Effects of Applying Different Resonance Amplitude on the Performance of the Impedance-Based Health Monitoring Technique Subjected to Damage

open access: yesSensors, 2018
Smart materials such as piezoelectric transducers can be used for monitoring the health of building structures. In this study, a structural health monitoring technique known as the electromechanical impedance (EMI) method is investigated.
Wongi S. Na   +3 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Airports—Energy and Sustainability Perspectives

open access: yesEnergies
This study explored the role of airports in the aviation sector from both energy and sustainability perspectives, highlighting their potential contribution to reducing the sector’s carbon emissions.
Musadag El Zein   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

On the Influence of PV Cell and Diode Configurations on the Performance of a CPVT Collector: A Comparative Analysis

open access: yesEnergies
Concentrating photovoltaic-thermal (CPVT) collectors use reflective surfaces to focus sunlight onto a smaller receiver area, increasing thermal energy output while maintaining annual energy efficiency.
João Gomes   +4 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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