Results 51 to 60 of about 1,491,266 (280)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Towards Sustainable Building: Case Study on Romania

open access: yesRomanian Economic Journal, 2016
The purpose of this article is to analyze the actual situation of the green buildings in our country but also the degree in which the real estate developers are involved in such projects.
Ana Maria Marinoiu   +2 more
doaj  

Building Sustainable Partnerships to Promote Women's Political Representation in Southeast Asian Region [PDF]

open access: yes, 2012
In a democratic country, gender equality is an element that needs to be guaranteed by the government, particularly in political positions such as in government offices, political parties, and other decision-making institutions.
Adisti Ikayanti, Andrew Thornley
core   +1 more source

Thermal analysis and energy-efficient solutions to preserve listed building façades. The INA-Casa building heritage [PDF]

open access: yes, 2017
Energy efficiency of building heritage derived from pre-regulation period is one of the most debated topics in Europe. Building facades, through opaque walls and thermal bridges, are a major source of transmission heat losses and require sustainable and ...
Cecere, Carlo   +2 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Hygrothermal response of masonry facades with vapour-tight or capillary-active internal insulation under current and future climate scenarios

open access: yesBuilt Heritage
Interior thermal insulation has been widely used to improve energy efficiency and indoor comfort of historic buildings. However, traditional vapour-tight insulation materials strongly influence the hygrothermal behaviour of facades, which may lead to ...
Xinyuan Dang   +3 more
doaj   +1 more source

Pressure equalisation as design strategy for watertightness [PDF]

open access: yes, 2008
Due to rising energy prices and a higher ecological awareness there is a growing attention for energy efficiency and sustainability in building construction.
Van Den Bossche, Nathan
core  

Sustainable and Healthy Buildings [PDF]

open access: yesIndoor and Built Environment, 2010
Nowadays, awareness and understanding on health and well-being related to various built-environments has become a part of the responsibility of architectural designers and scientists. It was in this context that the Center for Sustainable Healthy Buildings (CSHeB) at Kyung Hee University has been nominated as an Engineering Research Center (ERC) of an ...
openaire   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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