Results 31 to 40 of about 1,046,669 (303)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Study on the influencing factors of photovoltaic siting in coal mining subsidence areas–taking Shanxi Province as an example

Scientific Reports
Developing photovoltaic (PV) projects in coal mining subsidence areas represents a strategic pathway to improving land use efficiency and accelerating the transition to renewable energy.
Yan Lu, Yu Yan, Mengyao Wang, Long Zhou
doaj   +1 more source

Street Verge in Transition: A Study of Community Drivers and Local Policy Setting for Urban Greening in Perth, Western Australia

Urban Science, 2022
The United Nations’ Sustainable Development Goals (SDGs) are regarded as the key policy agenda for national, regional, and local government to combat climate change impacts and promote sustainable development.
Shania Hunt, Jeremy Maher, Mohammad Shahidul Hasan Swapan, Atiq Zaman   +3 more
doaj   +1 more source

City enhancement beyond the notion of “sustainable city”: introduction to integrated assessment for city enhancement (iACE) toolkit [PDF]

, 2016
Over the course of past three decades, many researchers questioned the oxymoron characteristics of sustainable city. It is, therefore, uncertain that to what extend cities can actually be sustainable or are they sustainable at all.
Ali Cheshmehzangi, Blassingame, Doughty, Elert, Register, Souza Santos, Wilson, Wong   +7 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

An Assessment Model for Sustainable Cities Using Crowdsourced Data Based on General System Theory: A Design Science Methodology Approach

Smart Cities, 2023
In the quest to understand urban ecosystems, traditional evaluation techniques often fall short due to incompatible data sources and the absence of comprehensive, real-time data.
Usman Ependi, Adian Fatchur Rochim, Adi Wibowo   +2 more
doaj   +1 more source

Disentangling urban sustainability: the Flemish City Monitor acknowledges complexity [PDF]

, 2010
Nowadays, cities have to deal with complexity. In this article we argue that the City Monitor for Sustainable Urban Development in the Flanders (Belgium) acknowledges complexity.
Block, Thomas, Van Assche, Joke
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The role of urban living labs in a smart city [PDF]

, 2014
In a rapidly changing socio-technical environment cities are increasingly seen as main drivers for change. Against this backdrop, this paper studies the emerging Urban Living Lab and Smart City concepts from a project based perspective, by assessing a ...
Baccarne, Bastiaan, De Marez, Lieven, Mechant, Peter, Schuurman, Dimitri   +3 more
core  

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source