Results 71 to 80 of about 1,116,131 (332)

Building the future: integrating building information management and environmental assessment methodologies [PDF]

open access: yes, 2012
The demand for sustainable buildings is increasing driven in part by legislation, rising energy costs and growing environmental concerns amongst consumers.
Alwan, Zaid, Hope, Alex
core  

Towards more sustainable construction–application of superabsorbent polymers in cementitious matrices with reduced carbon footprint [PDF]

open access: yes, 2018
Construction industry is constantly searching for sustainable innovations to mitigate negative environmental impacts. Ground granulated blast-furnace slag (GGBS) is a well-known supplementary cementitious material which contributes to reduction of energy
Alekrish   +20 more
core   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Attorney Fee Shifting: A Bibliography [PDF]

open access: yes, 1984
Marmara Sea and Black Sea connected with renowned Bosporus surround Istanbul, the city, which owns the privilege of bridging Europe and Asia. Besides such inland seas; forests and wetlands fragmented around and in the city maintain the natural cycle in ...
Christie, Kathryn M.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Pressure equalisation as design strategy for watertightness [PDF]

open access: yes, 2008
Due to rising energy prices and a higher ecological awareness there is a growing attention for energy efficiency and sustainability in building construction.
Van Den Bossche, Nathan
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Biogenic carbon in buildings: a critical overview of LCA methods

open access: yesBuildings & Cities, 2020
The increasing pressure to reduce greenhouse gas emissions from buildings has motivated specialists to develop low-carbon products incorporating bio-based materials.
Endrit Hoxha   +7 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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