Results 71 to 80 of about 5,154,633 (280)

Sustainable cement mixtures based on sediments as a filler [PDF]

open access: yesMATEC Web of Conferences
For several years, research has been devoted to the issue of abiotic reuse of excavated bottom sediments from waterways, reservoirs, harbors and estuaries in the construction industry.
Junakova Natalia   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Sustainable subdivisions – ventilation data analysis [PDF]

open access: yes, 2008
This project, as part of a broader Sustainable Sub-divisions research agenda, addresses the role of natural ventilation in reducing the use of energy required to cool ...

core  

Sustained resilience as a unifying property of cities and the built environment

open access: yesnpj Urban Sustainability
The built environment evolves, deteriorates and regenerates over time, yet resilience is commonly reduced to discrete event-based recovery while long-term performance is treated through sustainability.
Stergios-Aristoteles Mitoulis   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Green, healthy and fair : a review of government’s role in supporting sustainable supermarket food [PDF]

open access: yes, 2012
Green, Healthy and Fair is the Sustainable Development Commission's review of the Government’s role in enabling supermarkets to deliver a sustainable food system in the UK.Publisher ...
Sustainable Development Commission
core   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Sustainable subdivisions – ventilation monitoring [PDF]

open access: yes, 2006
Australia’s current pattern of residential development is typified by relatively low-density\ud subdivision of land and highlights the necessity for development to be more sustainable to\ud avoid unnecessary demand on natural resources and to prevent ...

core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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