Results 61 to 70 of about 20,450 (297)

The possible role of business organisations in sustainable development: approaches, boundaries, future directions [PDF]

open access: yes, 2014
It is increasingly evident that human development is proceeding in an unsustainable manner, and that large business organisations are significantly complicit in this process.
O'Dochartaigh, Aideen
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Pathways to the sustainable development goals [PDF]

open access: yes, 2016
The State of CSR series is the largest ongoing research study of corporate social responsibility (CSR) practices, trends and capabilities in Australia and New Zealand.
Australian Centre for Corporate Social Responsibility
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

“Sustainable Growth, New Knowledge and Corporate Income Taxes” [PDF]

open access: yes, 2020
This paper argues that economic growth is sustainable, that new knowledge is the key to that growth and that corporate income taxes are an obstacle to sustainable growth because of their effect on knowledge production.
Mark Smith (274792)
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Sustainable growth rate in the strategic analysis of brewery industry [PDF]

open access: yes
An analysis of sustainable growth rate could considerably improve an assessment of Strategic Business Unit’s potential. The sustainable growth rate analysis enabled us to compare a possible growth rate within the brewery industry with a growth rate that ...
Slonski, Tomasz   +1 more
core   +1 more source

Corporate social responsibility in forestry

open access: yesJournal of Forest Science, 2019
In Slovakia the topic of socially responsible business has been little reviewed and described, both theoretically and practically. The article highlights the differences in the definition and characteristics of Corporate social responsibility (CSR) as ...
Iveta Hajdúchová   +2 more
doaj   +1 more source

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