Results 141 to 150 of about 11,470,632 (278)

Sustainable Design Approach for Modeling Bioprocesses from Laboratory toward Commercialization: Optimizing Chitosan Production. [PDF]

Polymers (Basel), 2021
Meramo S, González-Delgado ÁD, Sukumara S, Fajardo WS, León-Pulido J.   +4 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A space syntax approach to sustainable design for public spaces in historic cities. [PDF]

PLoS One
Zhu Y, Huang L, Xie C, Chen W.
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Sustainable Design Reuse: Integrating Biomimicry and Parametric Thinking in Architectural Education. [PDF]

Biomimetics (Basel)
Semlali A, Tamzini S, Cazacova L.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Fabrication of Transparent Pt-TiO2 Sol and Its Photocatalytic Activity for Hydrogen Evolution

ACS Omega
Naoto Nishiyama, Kyouhei Oono, Hiroto Takeuchi, Mariko Yukimoto, Yutaka Takaguchi   +4 more
doaj   +1 more source

Sustainable Design of High-Performance Polyurethanes Using Medium-Chain-Length Polyhydroxyalkanoates. [PDF]

Polymers (Basel)
Nikodinovic-Runic J, Rao CV, Guzik M, Zimowska M, Milivojevic D, Ponjavic M.   +5 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design. [PDF]

Adv Sci (Weinh)
Kamatchi Sundaram A, Chakraborty M, Devathi SMK, Prusty BP, Batra R.   +4 more
europepmc   +1 more source