Results 91 to 100 of about 3,268,438 (293)

PROSPECTS FOR THE DEVELOPMENT OF HIGHER EDUCATION: EDUCOLOGICAL ASPECTS

open access: yesНеперервна професійна освіта: теорія та практика, 2023
The article is devoted to the analysis of prospects for the development of education from the point of view of educology and futurology. The author emphasizes that the idea of the future has gone from science fiction to modern expectations and ...
Olga Melnychenko
doaj   +1 more source

Healthy Diets from Sustainable Food Systems [PDF]

open access: yes, 2015
Healthy Diets from Sustainable Food Systems: Integrated Indicators, GlobalFood Database and EAT Report Frank Rijsberman, CEO CGIAR ...
CGIAR Consortium Office   +2 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Camelids and sustainable development [PDF]

open access: yes, 2015
Face to the global changes and new climatic constraints, the camel farming is confronted to new challenges, first to contribute to the “livestock revolution” (for reaching the requirements of a growing human population), especially in remote places of ...
Faye, Bernard
core  

Universities, regional policy and the knowledge economy [PDF]

open access: yes, 2004
This article focuses on the spatial clustering dimension of new information and communications technology (ICT)-driven economic activity based on knowledge industries and especially the tacit knowledge synergies to be achieved through networking in ...
Association of Greater Manchester Authorities (AGMA)   +4 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

‘Bring the whole tithe into the storehouse’: The tithe and sustainable development in Ghanaian Pentecostalism

open access: yesAfrican Journal of Pentecostal Studies
Background: This article explores the Church of Pentecost’s (CoP) theology of tithes and its intersection with sustainable development in Ghana. This research is grounded on the theory that the CoP through the Pentecost Social Services (PENTSOS) as well ...
Emmanuel A. Kenin
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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