Results 131 to 140 of about 3,268,438 (293)
A Plan for the Economic Development for the Gaza Strip: Free Industrial Zone on Land and on Artificial Islands [PDF]
, 2004 Presents a plan for the sustainable economic development of the Gaza Strip with primary concerns discussing job creation, sustainable economic development, and environmental ...
Frankel, Ernst
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Integration perspectives for improving regional policy in rural areas of Bulgaria
Agricultural and Resource EconomicsPurpose. The purpose of the research is to determine the degree of implementation of specific regional policies in rural areas in the context of Bulgaria’s integration into the European Union through the prospects of the changing economic situation and ...
Petar Borisov +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Sustainable Development in Southern Africa: Progress in Addressing the Challenges [PDF]
, 2005 This paper reviews the progress made in establishing institutional framework for sustainable development in Southern Africa, identifies the major successes and challenges in implementing sustainable development policies and programs and suggests ...
Gladys B. Mutangadura
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
International Journal of Chemical EngineeringPolyethylene (PE) accounts for approximately 40% of total global plastic production, yet PE waste remains an underutilized feedstock. Meanwhile, activated carbon (AC) derived primarily from coconut shells (CS), the most popular source, is usually ...
Junaid Saleem +3 more
doaj +1 more source
Sustainable Development And Demography [PDF]
Sustainable development is another philosophy of human society, where the main purpose is to ensure life on earth as a period of time. At the heart of this new philosophy is man wherever he occupied on earth.
Ioan PANA, Viorica PANA
core
SUSTAINABLE DEVELOPMENT OF TERRITORIES OF MINING REGIONS [PDF]
, 2018 Developing innovative technologies of mining coal seams and increasing the competitiveness of coal produced and providing further diversification of the mine using the "post-mining" concept as the basis for sustainable ...
DUBOVIK, Oleksandr, LOHUNOVA, Oleksandra
core
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source