Results 111 to 120 of about 32,804 (295)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Sustainable Fashion: Breaking the Myth
, 2017 Sustainable fashion is "clothing, shoes, and accessories that are manufactured, marketed and used in the most sustainable manner possible, taking into account both environmental and socioeconomic aspects" (Green Strategy, 2017).
Ward, Rachel Allyn
core
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Genesis, Features and Prospects for the Development of Digital Fashion
Preservation, Digital Technology & CultureIn the modern world, the fashion industry is constantly evolving, and digital technologies are having an increasingly significant impact on its development.
Biliakovych Liana +4 more
doaj +1 more source
Sustainable Brand Extensions of Fast Fashion Brands; the Influence on Parent Brand Attitude
International Journal of Advanced Business StudiesFashion industry to be one of the largest consumer industries & the second most polluting in the world because only a few industries confront as many sustainability issues as the fashion industry.
Shreyansh Umesh Sagare, Najla Shafighi
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
SUSTAINABLE LEATHER FOR SUSTAINABLE FASHION
, 2021 Sustainability has today assumed a centrality in the fashion industry. Conceria Nuvolari is an Italian innovative SME founded in 2009 and specialised in the production and sale of animal leathers. Since 2015 Conceria Nuvolari has been in the search for more sustainable materials, to obtain a leather product that could meet the needs of a transforming ...
Dotelli G. +4 more
openaire +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source